1ypj
From Proteopedia
(Difference between revisions)
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|PDB= 1ypj |SIZE=350|CAPTION= <scene name='initialview01'>1ypj</scene>, resolution 1.78Å | |PDB= 1ypj |SIZE=350|CAPTION= <scene name='initialview01'>1ypj</scene>, resolution 1.78Å | ||
|SITE= | |SITE= | ||
| - | |LIGAND= <scene name='pdbligand=UIB:(1R,3AS,4R,8AS,8BR)-4-{5-(PHENYL[1,3]DIOXOL-5-YLMETHYL)-4-ETHYL-2,3,3-TRIMETHYL-6-OXO-OCTAHYDRO-PYRROLO[3,4-C]PYRROL-1-YL}-BENZAMIDINE'>UIB</scene> | + | |LIGAND= <scene name='pdbligand=TYS:SULFONATED+TYROSINE'>TYS</scene>, <scene name='pdbligand=UIB:(1R,3AS,4R,8AS,8BR)-4-{5-(PHENYL[1,3]DIOXOL-5-YLMETHYL)-4-ETHYL-2,3,3-TRIMETHYL-6-OXO-OCTAHYDRO-PYRROLO[3,4-C]PYRROL-1-YL}-BENZAMIDINE'>UIB</scene> |
| - | |ACTIVITY= [http://en.wikipedia.org/wiki/Thrombin Thrombin], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.21.5 3.4.21.5] | + | |ACTIVITY= <span class='plainlinks'>[http://en.wikipedia.org/wiki/Thrombin Thrombin], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.21.5 3.4.21.5] </span> |
|GENE= | |GENE= | ||
| + | |DOMAIN= | ||
| + | |RELATEDENTRY=[[1y3x|1Y3X]], [[1yp9|1YP9]], [[1ype|1YPE]], [[1ypg|1YPG]] | ||
| + | |RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1ypj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ypj OCA], [http://www.ebi.ac.uk/pdbsum/1ypj PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1ypj RCSB]</span> | ||
}} | }} | ||
'''Thrombin Inhibitor Complex''' | '''Thrombin Inhibitor Complex''' | ||
| - | |||
| - | ==Disease== | ||
| - | Known diseases associated with this structure: Dysprothrombinemia OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=176930 176930]], Hyperprothrombinemia OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=176930 176930]], Hypoprothrombinemia OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=176930 176930]] | ||
==About this Structure== | ==About this Structure== | ||
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[[Category: Klebe, G.]] | [[Category: Klebe, G.]] | ||
[[Category: Obst-Sander, U.]] | [[Category: Obst-Sander, U.]] | ||
| - | [[Category: UIB]] | ||
[[Category: 6 stranded beta-sheet]] | [[Category: 6 stranded beta-sheet]] | ||
[[Category: barrel]] | [[Category: barrel]] | ||
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[[Category: thrombin]] | [[Category: thrombin]] | ||
| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 31 01:16:51 2008'' |
Revision as of 22:16, 30 March 2008
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| , resolution 1.78Å | |||||||
|---|---|---|---|---|---|---|---|
| Ligands: | , | ||||||
| Activity: | Thrombin, with EC number 3.4.21.5 | ||||||
| Related: | 1Y3X, 1YP9, 1YPE, 1YPG
| ||||||
| Resources: | FirstGlance, OCA, PDBsum, RCSB | ||||||
| Coordinates: | save as pdb, mmCIF, xml | ||||||
Thrombin Inhibitor Complex
About this Structure
1YPJ is a Protein complex structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.
Reference
A simple protocol to estimate differences in protein binding affinity for enantiomers without prior resolution of racemates., Fokkens J, Klebe G, Angew Chem Int Ed Engl. 2006 Jan 30;45(6):985-9. PMID:16374786
Page seeded by OCA on Mon Mar 31 01:16:51 2008
