Urea transporter

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Line 1: Line 1:
 +
<StructureSection load='' size='450' side='right' caption='Urea transporter trimer ([[3me1]]' scene='Urea_transporter/3k3fdefault/1' pspeed='8'>
 +
[[Image:3k3f.png|left|200px]]
[[Image:3k3f.png|left|200px]]
Line 6: Line 8:
==About this Structure==
==About this Structure==
-
{{Structure
+
 
-
|PDB= 3me1 |SIZE=400|SCENE= |CAPTION=Urea transporter trimer ([[3me1]]); (<scene name='Urea_transporter/3k3fdefault/1'>initial scene</scene>)
+
-
|SITE=
+
-
|LIGAND=
+
-
|ACTIVITY=
+
-
|GENE=
+
-
|DOMAIN=
+
-
|RELATEDENTRY=
+
-
|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3k3f FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3k3f OCA], [http://www.ebi.ac.uk/pdbsum/3k3f PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=3k3f RCSB]</span>
+
-
}}
+
To help give a better idea of how the urea transporter is oriented in the membrane lipid bilayer, <scene name='Urea_transporter/Opm_3k3f/3'>a slab representative of hydrophobic core of the lipid bilayer</scene> as calculated by the [http://opm.phar.umich.edu/protein.php?pdbid=3kg2 Orientations of Proteins in Membranes database](University of Michigan, USA) is shown with the red patch of spheres indicating the boundary of the hydrophobic core closet to the outside of the cell and the dark blue patch of spheres indicating the boundary closest to the inside of the cell.
To help give a better idea of how the urea transporter is oriented in the membrane lipid bilayer, <scene name='Urea_transporter/Opm_3k3f/3'>a slab representative of hydrophobic core of the lipid bilayer</scene> as calculated by the [http://opm.phar.umich.edu/protein.php?pdbid=3kg2 Orientations of Proteins in Membranes database](University of Michigan, USA) is shown with the red patch of spheres indicating the boundary of the hydrophobic core closet to the outside of the cell and the dark blue patch of spheres indicating the boundary closest to the inside of the cell.
[[Image:Opm_periplasmic_topology.gif]] <!--I got this from Eric Martz's [[Mechanosensitive channels: opening and closing]]-->
[[Image:Opm_periplasmic_topology.gif]] <!--I got this from Eric Martz's [[Mechanosensitive channels: opening and closing]]-->
 +
</StructureSection>
==3D structures of urea transporter==
==3D structures of urea transporter==

Revision as of 03:47, 16 October 2017

Urea transporter trimer (3me1

Drag the structure with the mouse to rotate

Contents

3D structures of urea transporter

Update February 2013

3k3f, 3me1 – DvUT – Desulfovibrio vulgaris
3m6e – DvUT (mutant)
3k3g – DvUT + dimethylurea
4ezc – bUT + ceramide - bovine
4ezd – bUT + ceramide + selenourea

Reference for the structure

  • Levin EJ, Quick M, Zhou M. Crystal structure of a bacterial homologue of the kidney urea transporter. Nature. 2009 Dec 10;462(7274):757-61. Epub . PMID:19865084 doi:10.1038/nature08558

See Also

  • Knepper MA, Mindell JA. Structural biology: Molecular coin slots for urea. Nature. 2009 Dec 10;462(7274):733-4. PMID:20010678 doi:10.1038/462733a

Reference

Page started with original page on 3k3f seeded by OCA on Thu Jan 28 14:58:46 2010

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Wayne Decatur, David Canner, Jaime Prilusky, Joel L. Sussman

Retrieved from "http://52.214.119.220/wiki/index.php/Urea_transporter"
Personal tools