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WD repeat-containing protein
From Proteopedia
(Difference between revisions)
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**[[3smr]], [[3ur4]], [[4ia9]], [[4qqe]], [[4ql1]], [[5eal]], [[5eam]], [[5eap]], [[5ear]] – hWDR5 + piperazine derivative<br /> | **[[3smr]], [[3ur4]], [[4ia9]], [[4qqe]], [[4ql1]], [[5eal]], [[5eam]], [[5eap]], [[5ear]] – hWDR5 + piperazine derivative<br /> | ||
**[[2cnx]], [[2co0]], [[2h6k]], [[2h6n]], [[2h6q]], [[2h13]], [[2h9m]], [[2h9n]], [[2h9p]], [[2g99]], [[2g9a]], [[2o9k]], [[3psl]], [[4a7j]] – hWDR5 + histone H3 peptide<br /> | **[[2cnx]], [[2co0]], [[2h6k]], [[2h6n]], [[2h6q]], [[2h13]], [[2h9m]], [[2h9n]], [[2h9p]], [[2g99]], [[2g9a]], [[2o9k]], [[3psl]], [[4a7j]] – hWDR5 + histone H3 peptide<br /> | ||
| - | **[[ | + | **[[5vfc]] – hWDR5 + inhibitor<br /> |
**[[4gm3]], [[4gm8]], [[4gm9]], [[4gmb]] – hWDR5 + peptide inhibitor<br /> | **[[4gm3]], [[4gm8]], [[4gm9]], [[4gmb]] – hWDR5 + peptide inhibitor<br /> | ||
**[[2xl2]], [[2xl3]] – hWDR5 + retinoblastoma-binding protein 5 peptide<br /> | **[[2xl2]], [[2xl3]] – hWDR5 + retinoblastoma-binding protein 5 peptide<br /> | ||
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**[[4cy2]] – hWDR5 + KAT8 regulatory NSL complex subunit 1 peptide<br /> | **[[4cy2]] – hWDR5 + KAT8 regulatory NSL complex subunit 1 peptide<br /> | ||
**[[4y7r]] – hWDR5 + Myc MbIIIb peptide<br /> | **[[4y7r]] – hWDR5 + Myc MbIIIb peptide<br /> | ||
| - | **[[3uvk]], [[3uvl]], [[3uvm]], [[3uvn]], [[3uvo]], [[4erq]], [[4ery]], [[4es0]], [[4esg]], [[4ewr]], [[5sxm]] – hWDR5 + MLL peptide<br /> | + | **[[3eg6]], [[3emh]], [[3uvk]], [[3uvl]], [[3uvm]], [[3uvn]], [[3uvo]], [[4erq]], [[4ery]], [[4es0]], [[4esg]], [[4ewr]], [[5sxm]] – hWDR5 + MLL peptide<br /> |
**[[4erz]] – hWDR5 + MLL4<br /> | **[[4erz]] – hWDR5 + MLL4<br /> | ||
**[[3p4f]] – hWDR5 + retinoblastoma-binding protein 5 peptide + MLL peptide<br /> | **[[3p4f]] – hWDR5 + retinoblastoma-binding protein 5 peptide + MLL peptide<br /> | ||
Revision as of 22:07, 16 October 2017
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3D Structures of WD-repeat protein
Updated on 16-October-2017
References
- ↑ Li D, Roberts R. WD-repeat proteins: structure characteristics, biological function, and their involvement in human diseases. Cell Mol Life Sci. 2001 Dec;58(14):2085-97. PMID:11814058
- ↑ Gan Q, Thiebaud P, Theze N, Jin L, Xu G, Grant P, Owens GK. WD repeat-containing protein 5, a ubiquitously expressed histone methyltransferase adaptor protein, regulates smooth muscle cell-selective gene activation through interaction with pituitary homeobox 2. J Biol Chem. 2011 Jun 17;286(24):21853-64. doi: 10.1074/jbc.M111.233098. Epub, 2011 Apr 28. PMID:21531708 doi:http://dx.doi.org/10.1074/jbc.M111.233098
- ↑ Tullio-Pelet A, Salomon R, Hadj-Rabia S, Mugnier C, de Laet MH, Chaouachi B, Bakiri F, Brottier P, Cattolico L, Penet C, Begeot M, Naville D, Nicolino M, Chaussain JL, Weissenbach J, Munnich A, Lyonnet S. Mutant WD-repeat protein in triple-A syndrome. Nat Genet. 2000 Nov;26(3):332-5. PMID:11062474 doi:http://dx.doi.org/10.1038/81642
- ↑ Schuetz A, Allali-Hassani A, Martin F, Loppnau P, Vedadi M, Bochkarev A, Plotnikov AN, Arrowsmith CH, Min J. Structural basis for molecular recognition and presentation of histone H3 by WDR5. EMBO J. 2006 Sep 20;25(18):4245-52. Epub 2006 Aug 31. PMID:16946699
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