5wj5
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==cryo-EM of a lysosomal protein== | |
| - | + | <StructureSection load='5wj5' size='340' side='right' caption='[[5wj5]], [[Resolution|resolution]] 3.70Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[5wj5]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5WJ5 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5WJ5 FirstGlance]. <br> | |
| - | + | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5wj5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5wj5 OCA], [http://pdbe.org/5wj5 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5wj5 RCSB], [http://www.ebi.ac.uk/pdbsum/5wj5 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5wj5 ProSAT]</span></td></tr> | |
| - | [[Category: | + | </table> |
| + | == Disease == | ||
| + | [[http://www.uniprot.org/uniprot/MCLN1_HUMAN MCLN1_HUMAN]] Mucolipidosis type 4. The disease is caused by mutations affecting the gene represented in this entry. | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/MCLN1_HUMAN MCLN1_HUMAN]] Cation channel probably playing a role in the endocytic pathway and in the control of membrane trafficking of proteins and lipids. Could play a major role in Ca(2+) transport regulating lysosomal exocytosis.<ref>PMID:12459486</ref> <ref>PMID:14749347</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Li, X]] | ||
[[Category: Schmiege, P]] | [[Category: Schmiege, P]] | ||
| - | [[Category: | + | [[Category: Human trpml1]] |
| + | [[Category: Membrane protein]] | ||
Revision as of 07:19, 18 October 2017
cryo-EM of a lysosomal protein
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