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2pgz
From Proteopedia
(Difference between revisions)
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==Crystal structure of Cocaine bound to an ACh-Binding Protein== | ==Crystal structure of Cocaine bound to an ACh-Binding Protein== | ||
<StructureSection load='2pgz' size='340' side='right' caption='[[2pgz]], [[Resolution|resolution]] 1.76Å' scene=''> | <StructureSection load='2pgz' size='340' side='right' caption='[[2pgz]], [[Resolution|resolution]] 1.76Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[2pgz]] is a 5 chain structure with sequence from [http://en.wikipedia.org/wiki/Aplca Aplca]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PGZ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2PGZ FirstGlance]. <br> | <table><tr><td colspan='2'>[[2pgz]] is a 5 chain structure with sequence from [http://en.wikipedia.org/wiki/Aplca Aplca]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PGZ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2PGZ FirstGlance]. <br> | ||
| - | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BMA:BETA-D-MANNOSE'>BMA</scene>, <scene name='pdbligand=COC:COCAINE'>COC</scene>, <scene name='pdbligand= | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BMA:BETA-D-MANNOSE'>BMA</scene>, <scene name='pdbligand=COC:COCAINE'>COC</scene>, <scene name='pdbligand=MAN:ALPHA-D-MANNOSE'>MAN</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=PG4:TETRAETHYLENE+GLYCOL'>PG4</scene></td></tr> |
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">synthetic ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=6500 APLCA])</td></tr> | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">synthetic ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=6500 APLCA])</td></tr> | ||
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2pgz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2pgz OCA], [http://pdbe.org/2pgz PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2pgz RCSB], [http://www.ebi.ac.uk/pdbsum/2pgz PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2pgz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2pgz OCA], [http://pdbe.org/2pgz PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2pgz RCSB], [http://www.ebi.ac.uk/pdbsum/2pgz PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2pgz ProSAT]</span></td></tr> |
</table> | </table> | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
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<text>to colour the structure by Evolutionary Conservation</text> | <text>to colour the structure by Evolutionary Conservation</text> | ||
</jmolCheckbox> | </jmolCheckbox> | ||
| - | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/ | + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2pgz ConSurf]. |
<div style="clear:both"></div> | <div style="clear:both"></div> | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
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</div> | </div> | ||
<div class="pdbe-citations 2pgz" style="background-color:#fffaf0;"></div> | <div class="pdbe-citations 2pgz" style="background-color:#fffaf0;"></div> | ||
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| - | ==See Also== | ||
| - | *[[Acetylcholine binding protein|Acetylcholine binding protein]] | ||
== References == | == References == | ||
<references/> | <references/> | ||
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[[Category: Benzodiazepine]] | [[Category: Benzodiazepine]] | ||
[[Category: Choline binding protein]] | [[Category: Choline binding protein]] | ||
| + | [[Category: Choline-binding protein]] | ||
[[Category: Cocaine]] | [[Category: Cocaine]] | ||
[[Category: Galanthamine]] | [[Category: Galanthamine]] | ||
[[Category: Nicotinic acetycholine receptor]] | [[Category: Nicotinic acetycholine receptor]] | ||
[[Category: Non-competitive inhibitor]] | [[Category: Non-competitive inhibitor]] | ||
Revision as of 09:25, 18 October 2017
Crystal structure of Cocaine bound to an ACh-Binding Protein
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