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2q6b

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==Design and synthesis of novel, conformationally restricted HMG-COA reductase inhibitors==
==Design and synthesis of novel, conformationally restricted HMG-COA reductase inhibitors==
<StructureSection load='2q6b' size='340' side='right' caption='[[2q6b]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
<StructureSection load='2q6b' size='340' side='right' caption='[[2q6b]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">HMGCR ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">HMGCR ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Hydroxymethylglutaryl-CoA_reductase_(NADPH) Hydroxymethylglutaryl-CoA reductase (NADPH)], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.1.34 1.1.1.34] </span></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Hydroxymethylglutaryl-CoA_reductase_(NADPH) Hydroxymethylglutaryl-CoA reductase (NADPH)], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.1.34 1.1.1.34] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2q6b FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2q6b OCA], [http://pdbe.org/2q6b PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2q6b RCSB], [http://www.ebi.ac.uk/pdbsum/2q6b PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2q6b FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2q6b OCA], [http://pdbe.org/2q6b PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2q6b RCSB], [http://www.ebi.ac.uk/pdbsum/2q6b PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2q6b ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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</div>
</div>
<div class="pdbe-citations 2q6b" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 2q6b" style="background-color:#fffaf0;"></div>
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==See Also==
 
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*[[HMG-CoA Reductase|HMG-CoA Reductase]]
 
== References ==
== References ==
<references/>
<references/>

Revision as of 09:39, 18 October 2017

Design and synthesis of novel, conformationally restricted HMG-COA reductase inhibitors

2q6b, resolution 2.00Å

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