2q6c
From Proteopedia
(Difference between revisions)
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==Design and synthesis of novel, conformationally restricted HMG-COA reductase inhibitors== | ==Design and synthesis of novel, conformationally restricted HMG-COA reductase inhibitors== | ||
<StructureSection load='2q6c' size='340' side='right' caption='[[2q6c]], [[Resolution|resolution]] 2.00Å' scene=''> | <StructureSection load='2q6c' size='340' side='right' caption='[[2q6c]], [[Resolution|resolution]] 2.00Å' scene=''> | ||
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">HMGCR ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr> | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">HMGCR ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr> | ||
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Hydroxymethylglutaryl-CoA_reductase_(NADPH) Hydroxymethylglutaryl-CoA reductase (NADPH)], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.1.34 1.1.1.34] </span></td></tr> | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Hydroxymethylglutaryl-CoA_reductase_(NADPH) Hydroxymethylglutaryl-CoA reductase (NADPH)], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.1.34 1.1.1.34] </span></td></tr> | ||
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2q6c FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2q6c OCA], [http://pdbe.org/2q6c PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2q6c RCSB], [http://www.ebi.ac.uk/pdbsum/2q6c PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2q6c FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2q6c OCA], [http://pdbe.org/2q6c PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2q6c RCSB], [http://www.ebi.ac.uk/pdbsum/2q6c PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2q6c ProSAT]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
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<text>to colour the structure by Evolutionary Conservation</text> | <text>to colour the structure by Evolutionary Conservation</text> | ||
</jmolCheckbox> | </jmolCheckbox> | ||
| - | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/ | + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2q6c ConSurf]. |
<div style="clear:both"></div> | <div style="clear:both"></div> | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
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</div> | </div> | ||
<div class="pdbe-citations 2q6c" style="background-color:#fffaf0;"></div> | <div class="pdbe-citations 2q6c" style="background-color:#fffaf0;"></div> | ||
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| - | ==See Also== | ||
| - | *[[HMG-CoA Reductase|HMG-CoA Reductase]] | ||
== References == | == References == | ||
<references/> | <references/> | ||
Revision as of 09:39, 18 October 2017
Design and synthesis of novel, conformationally restricted HMG-COA reductase inhibitors
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