C-X-C motif chemokine
From Proteopedia
(Difference between revisions)
| Line 1: | Line 1: | ||
| - | + | ||
| + | <StructureSection load='1qg7' size='350' side='right' caption='CXCL12α dimer complex with sulfate (PDB code [[1qg7]]).' scene=''> | ||
'''C-X-C motif chemokine''' (CXCL) are small chemokines which contain the sequence Cys-X-Cys at their C-terminal. The CXCL are subdivided into 2 groups: ELR positive (containing Glu-Leu-Arg preceding the C-X-C) and ELR negative.<ref>PMID:16212895</ref><br /> | '''C-X-C motif chemokine''' (CXCL) are small chemokines which contain the sequence Cys-X-Cys at their C-terminal. The CXCL are subdivided into 2 groups: ELR positive (containing Glu-Leu-Arg preceding the C-X-C) and ELR negative.<ref>PMID:16212895</ref><br /> | ||
| Line 8: | Line 9: | ||
• '''CXCL12''' or '''Stromal-Derived-Factor-1''' (SDF1) has a role in angiogenesis, tumor metastasis and the migration of cells from the liver to the bone marrow during embryogenesis.<br /> | • '''CXCL12''' or '''Stromal-Derived-Factor-1''' (SDF1) has a role in angiogenesis, tumor metastasis and the migration of cells from the liver to the bone marrow during embryogenesis.<br /> | ||
• '''CXCL14''' or '''BRAK''' acts as chemotactic for monocytes and inhibits angiogenesis.<br /> | • '''CXCL14''' or '''BRAK''' acts as chemotactic for monocytes and inhibits angiogenesis.<br /> | ||
| - | + | </StructureSection> | |
== 3D Structures of C-X-C motif chemokine == | == 3D Structures of C-X-C motif chemokine == | ||
Revision as of 15:25, 19 October 2017
| |||||||||||
3D Structures of C-X-C motif chemokine
Updated on 19-October-2017
