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5tle

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'''Unreleased structure'''
 
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The entry 5tle is ON HOLD until Paper Publication
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==Fructose-1,6-bisphosphate aldolase from rabbit muscle in complex with the inhibitor 2-phosphate-naphthalene 6-bisphosphonate==
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<StructureSection load='5tle' size='340' side='right' caption='[[5tle]], [[Resolution|resolution]] 1.58&Aring;' scene=''>
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Authors: Heron, P.W., Sygusch, J.
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== Structural highlights ==
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<table><tr><td colspan='2'>[[5tle]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5TLE OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5TLE FirstGlance]. <br>
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Description: Fructose-1,6-bisphosphate aldolase from rabbit muscle in complex with the inhibitor 2-phosphate-naphthalene 6-bisphosphonate
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=RD1:{[6-(phosphonooxy)naphthalen-2-yl]methylene}bis(phosphonic+acid)'>RD1</scene></td></tr>
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[[Category: Unreleased Structures]]
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5tlh|5tlh]], [[5tlw|5tlw]], [[5tlz|5tlz]]</td></tr>
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[[Category: Heron, P.W]]
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Fructose-bisphosphate_aldolase Fructose-bisphosphate aldolase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.1.2.13 4.1.2.13] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5tle FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5tle OCA], [http://pdbe.org/5tle PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5tle RCSB], [http://www.ebi.ac.uk/pdbsum/5tle PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5tle ProSAT]</span></td></tr>
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</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/ALDOA_RABIT ALDOA_RABIT]] Plays a key role in glycolysis and gluconeogenesis. In addition, may also function as scaffolding protein.<ref>PMID:17329259</ref>
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== References ==
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<references/>
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__TOC__
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</StructureSection>
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[[Category: Fructose-bisphosphate aldolase]]
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[[Category: Heron, P W]]
[[Category: Sygusch, J]]
[[Category: Sygusch, J]]
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[[Category: Aldolase]]
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[[Category: Bisphosphonate]]
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[[Category: Complex]]
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[[Category: Inhibitor]]
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[[Category: Lyase]]
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[[Category: Lyase-inhibitor complex]]

Revision as of 07:15, 25 October 2017

Fructose-1,6-bisphosphate aldolase from rabbit muscle in complex with the inhibitor 2-phosphate-naphthalene 6-bisphosphonate

5tle, resolution 1.58Å

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