5vxc
From Proteopedia
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- | '''Unreleased structure''' | ||
- | + | ==Crystal Structure Analysis of human CLYBL in complex with free CoASH== | |
- | + | <StructureSection load='5vxc' size='340' side='right' caption='[[5vxc]], [[Resolution|resolution]] 1.87Å' scene=''> | |
- | + | == Structural highlights == | |
- | + | <table><tr><td colspan='2'>[[5vxc]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5VXC OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5VXC FirstGlance]. <br> | |
- | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=COA:COENZYME+A'>COA</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr> | |
- | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5vxc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5vxc OCA], [http://pdbe.org/5vxc PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5vxc RCSB], [http://www.ebi.ac.uk/pdbsum/5vxc PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5vxc ProSAT]</span></td></tr> |
+ | </table> | ||
+ | == Function == | ||
+ | [[http://www.uniprot.org/uniprot/CLYBL_HUMAN CLYBL_HUMAN]] Mitochondrial malate and beta-methylmalate synthase, which may be involved in vitamin B12 metabolism (Probable). Acts both as a malate synthase, converting glyoxylate and acetyl-CoA to malate. Also acts as a beta-methylmalate synthase by mediating conversion of glyoxylate and propionyl-CoA to beta-methylmalate (PubMed:24334609).<ref>PMID:24334609</ref> | ||
+ | == References == | ||
+ | <references/> | ||
+ | __TOC__ | ||
+ | </StructureSection> | ||
+ | [[Category: Shen, H]] | ||
+ | [[Category: Coash]] | ||
+ | [[Category: Formate form]] | ||
+ | [[Category: Lyase]] | ||
+ | [[Category: Trimer]] |
Revision as of 06:31, 1 November 2017
Crystal Structure Analysis of human CLYBL in complex with free CoASH
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Categories: Shen, H | Coash | Formate form | Lyase | Trimer