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3h0b

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==Discovery of aminoheterocycles as a novel beta-secretase inhibitor class==
==Discovery of aminoheterocycles as a novel beta-secretase inhibitor class==
<StructureSection load='3h0b' size='340' side='right' caption='[[3h0b]], [[Resolution|resolution]] 2.70&Aring;' scene=''>
<StructureSection load='3h0b' size='340' side='right' caption='[[3h0b]], [[Resolution|resolution]] 2.70&Aring;' scene=''>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">BACE, BACE1, beta-secretase, KIAA1149 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">BACE, BACE1, beta-secretase, KIAA1149 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Memapsin_2 Memapsin 2], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.23.46 3.4.23.46] </span></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Memapsin_2 Memapsin 2], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.23.46 3.4.23.46] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3h0b FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3h0b OCA], [http://pdbe.org/3h0b PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3h0b RCSB], [http://www.ebi.ac.uk/pdbsum/3h0b PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3h0b FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3h0b OCA], [http://pdbe.org/3h0b PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3h0b RCSB], [http://www.ebi.ac.uk/pdbsum/3h0b PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3h0b ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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</div>
</div>
<div class="pdbe-citations 3h0b" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 3h0b" style="background-color:#fffaf0;"></div>
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==See Also==
 
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*[[Beta secretase|Beta secretase]]
 
== References ==
== References ==
<references/>
<references/>
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[[Category: Memapsin 2]]
[[Category: Memapsin 2]]
[[Category: Allison, T J]]
[[Category: Allison, T J]]
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[[Category: Alternative splicing]]
[[Category: Aspartyl protease]]
[[Category: Aspartyl protease]]
[[Category: Disulfide bond]]
[[Category: Disulfide bond]]
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[[Category: Hydrolase]]
[[Category: Hydrolase]]
[[Category: Membrane]]
[[Category: Membrane]]
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[[Category: Polymorphism]]
[[Category: Protease]]
[[Category: Protease]]
[[Category: Transmembrane]]
[[Category: Transmembrane]]
[[Category: Zymogen]]
[[Category: Zymogen]]

Revision as of 07:17, 1 November 2017

Discovery of aminoheterocycles as a novel beta-secretase inhibitor class

3h0b, resolution 2.70Å

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