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3hit
From Proteopedia
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==Crystal structure of Saporin-L1 in complex with the dinucleotide inhibitor, a transition state analogue== | ==Crystal structure of Saporin-L1 in complex with the dinucleotide inhibitor, a transition state analogue== | ||
<StructureSection load='3hit' size='340' side='right' caption='[[3hit]], [[Resolution|resolution]] 2.29Å' scene=''> | <StructureSection load='3hit' size='340' side='right' caption='[[3hit]], [[Resolution|resolution]] 2.29Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[3hit]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Common_soapwort Common soapwort]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3HIT OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3HIT FirstGlance]. <br> | <table><tr><td colspan='2'>[[3hit]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Common_soapwort Common soapwort]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3HIT OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3HIT FirstGlance]. <br> | ||
| - | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=DYN:5-O-[(S)-{[(3R,4R)-1-[(4- | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=DYN:5-O-[(S)-{[(3R,4R)-1-[(4-amino-5H-pyrrolo[3,2-d]pyrimidin-7-yl)methyl]-4-({[(S)-hydroxy(3-hydroxypropoxy)phosphoryl]oxy}methyl)pyrrolidin-3-yl]oxy}(hydroxy)phosphoryl]-3-O-[(R)-hydroxy(4-hydroxybutoxy)phosphoryl]-2-O-methylguanosine'>DYN</scene></td></tr> |
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3hio|3hio]], [[3hiq|3hiq]], [[3his|3his]], [[3hiv|3hiv]], [[3hiw|3hiw]]</td></tr> | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3hio|3hio]], [[3hiq|3hiq]], [[3his|3his]], [[3hiv|3hiv]], [[3hiw|3hiw]]</td></tr> | ||
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/rRNA_N-glycosylase rRNA N-glycosylase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.2.22 3.2.2.22] </span></td></tr> | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/rRNA_N-glycosylase rRNA N-glycosylase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.2.22 3.2.2.22] </span></td></tr> | ||
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3hit FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3hit OCA], [http://pdbe.org/3hit PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3hit RCSB], [http://www.ebi.ac.uk/pdbsum/3hit PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3hit FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3hit OCA], [http://pdbe.org/3hit PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3hit RCSB], [http://www.ebi.ac.uk/pdbsum/3hit PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3hit ProSAT]</span></td></tr> |
</table> | </table> | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
Revision as of 07:38, 1 November 2017
Crystal structure of Saporin-L1 in complex with the dinucleotide inhibitor, a transition state analogue
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