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3hqr

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==PHD2:Mn:NOG:HIF1-alpha substrate complex==
==PHD2:Mn:NOG:HIF1-alpha substrate complex==
<StructureSection load='3hqr' size='340' side='right' caption='[[3hqr]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
<StructureSection load='3hqr' size='340' side='right' caption='[[3hqr]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[3hqr]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3HQR OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3HQR FirstGlance]. <br>
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<table><tr><td colspan='2'>[[3hqr]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3HQR OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3HQR FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene>, <scene name='pdbligand=OGA:N-OXALYLGLYCINE'>OGA</scene></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene>, <scene name='pdbligand=OGA:N-OXALYLGLYCINE'>OGA</scene></td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3hqu|3hqu]], [[2g1m|2g1m]]</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3hqu|3hqu]], [[2g1m|2g1m]]</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">PHD2 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">PHD2 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3hqr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3hqr OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3hqr RCSB], [http://www.ebi.ac.uk/pdbsum/3hqr PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3hqr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3hqr OCA], [http://pdbe.org/3hqr PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3hqr RCSB], [http://www.ebi.ac.uk/pdbsum/3hqr PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3hqr ProSAT]</span></td></tr>
</table>
</table>
== Disease ==
== Disease ==
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<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
</jmolCheckbox>
</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3hqr ConSurf].
<div style="clear:both"></div>
<div style="clear:both"></div>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
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<div class="pdbe-citations 3hqr" style="background-color:#fffaf0;"></div>
==See Also==
==See Also==
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*[[Factor inhibiting HIF|Factor inhibiting HIF]]
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*[[Molecular Playground/Prolyl Hydroxylase Domain (PHD) Enzyme|Molecular Playground/Prolyl Hydroxylase Domain (PHD) Enzyme]]
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*[[Hypoxia-inducible factor prolyl hydroxylase|Hypoxia-inducible factor prolyl hydroxylase]]
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*[[Prolyl hydroxylase domain|Prolyl hydroxylase domain]]
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== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Homo sapiens]]
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[[Category: Human]]
[[Category: Chowdhury, R]]
[[Category: Chowdhury, R]]
[[Category: McDonough, M A]]
[[Category: McDonough, M A]]
[[Category: Schofield, C J]]
[[Category: Schofield, C J]]
[[Category: Activator]]
[[Category: Activator]]
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[[Category: Alternative splicing]]
[[Category: Congenital erythrocytosis]]
[[Category: Congenital erythrocytosis]]
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[[Category: Cytoplasm]]
[[Category: Dioxygenase]]
[[Category: Dioxygenase]]
[[Category: Disease mutation]]
[[Category: Disease mutation]]
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[[Category: Oxidoreductase-transcription complex]]
[[Category: Oxidoreductase-transcription complex]]
[[Category: Phosphoprotein]]
[[Category: Phosphoprotein]]
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[[Category: Polymorphism]]
[[Category: S-nitrosylation]]
[[Category: S-nitrosylation]]
[[Category: Transcription]]
[[Category: Transcription]]
[[Category: Transcription regulation]]
[[Category: Transcription regulation]]
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[[Category: Ubl conjugation]]
[[Category: Vitamin c]]
[[Category: Vitamin c]]
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[[Category: Zinc]]
[[Category: Zinc-finger]]
[[Category: Zinc-finger]]

Revision as of 07:44, 1 November 2017

PHD2:Mn:NOG:HIF1-alpha substrate complex

3hqr, resolution 2.00Å

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