This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
5bw6
From Proteopedia
| Line 1: | Line 1: | ||
| + | |||
==Tryptophan Synthase from Salmonella typhimurium in complex with a single molecule of 2-({[4-(trifluoromethoxy)phenyl]carbonyl}amino)ethyl dihydrogen phosphate (F6) in the alpha-site.== | ==Tryptophan Synthase from Salmonella typhimurium in complex with a single molecule of 2-({[4-(trifluoromethoxy)phenyl]carbonyl}amino)ethyl dihydrogen phosphate (F6) in the alpha-site.== | ||
<StructureSection load='5bw6' size='340' side='right' caption='[[5bw6]], [[Resolution|resolution]] 1.82Å' scene=''> | <StructureSection load='5bw6' size='340' side='right' caption='[[5bw6]], [[Resolution|resolution]] 1.82Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[5bw6]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5BW6 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5BW6 FirstGlance]. <br> | + | <table><tr><td colspan='2'>[[5bw6]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_typhimurium"_loeffler_1892 "bacillus typhimurium" loeffler 1892]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5BW6 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5BW6 FirstGlance]. <br> |
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=F6F:2-{[4-(TRIFLUOROMETHOXY)BENZOYL]AMINO}ETHYL+DIHYDROGEN+PHOSPHATE'>F6F</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=PLP:PYRIDOXAL-5-PHOSPHATE'>PLP</scene></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=F6F:2-{[4-(TRIFLUOROMETHOXY)BENZOYL]AMINO}ETHYL+DIHYDROGEN+PHOSPHATE'>F6F</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=PLP:PYRIDOXAL-5-PHOSPHATE'>PLP</scene></td></tr> | ||
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4wx2|4wx2]], [[4y6g|4y6g]], [[4zqc|4zqc]], [[2clm|2clm]], [[2cle|2cle]], [[2clf|2clf]]</td></tr> | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4wx2|4wx2]], [[4y6g|4y6g]], [[4zqc|4zqc]], [[2clm|2clm]], [[2cle|2cle]], [[2clf|2clf]]</td></tr> | ||
| + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">trpA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=90371 "Bacillus typhimurium" Loeffler 1892]), trpB ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=90371 "Bacillus typhimurium" Loeffler 1892])</td></tr> | ||
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Tryptophan_synthase Tryptophan synthase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.2.1.20 4.2.1.20] </span></td></tr> | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Tryptophan_synthase Tryptophan synthase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.2.1.20 4.2.1.20] </span></td></tr> | ||
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5bw6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5bw6 OCA], [http://pdbe.org/5bw6 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5bw6 RCSB], [http://www.ebi.ac.uk/pdbsum/5bw6 PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5bw6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5bw6 OCA], [http://pdbe.org/5bw6 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5bw6 RCSB], [http://www.ebi.ac.uk/pdbsum/5bw6 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5bw6 ProSAT]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
| Line 23: | Line 25: | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| + | [[Category: Bacillus typhimurium loeffler 1892]] | ||
[[Category: Tryptophan synthase]] | [[Category: Tryptophan synthase]] | ||
[[Category: Caulkins, B G]] | [[Category: Caulkins, B G]] | ||
Revision as of 12:23, 6 November 2017
Tryptophan Synthase from Salmonella typhimurium in complex with a single molecule of 2-({[4-(trifluoromethoxy)phenyl]carbonyl}amino)ethyl dihydrogen phosphate (F6) in the alpha-site.
| |||||||||||
Categories: Bacillus typhimurium loeffler 1892 | Tryptophan synthase | Caulkins, B G | Dunn, M F | Fan, L | Hilario, E | Mueller, L J | Niks, D | Young, R P | Allosteric enzyme | Aromatic amino acid biosynthesis | Carbon-oxygen lyase | F6f | Inhibitor | Lyase-lyase inhibitor complex | Pyridoxal phosphate | Salmonella typhimurium | Transferase | Tryptophan biosynthesis
