5upz

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<StructureSection load='5upz' size='340' side='right' caption='[[5upz]], [[Resolution|resolution]] 1.27&Aring;' scene=''>
<StructureSection load='5upz' size='340' side='right' caption='[[5upz]], [[Resolution|resolution]] 1.27&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[5upz]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5UPZ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5UPZ FirstGlance]. <br>
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<table><tr><td colspan='2'>[[5upz]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/9hiv1 9hiv1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5UPZ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5UPZ FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=8HD:N~3~-{(2S,3R)-3-HYDROXY-4-[{[4-(HYDROXYMETHYL)PHENYL]SULFONYL}(2-METHYLPROPYL)AMINO]-1-PHENYLBUTAN-2-YL}-N~1~-METHYL-N~1~-[(4-METHYL-1,3-OXAZOL-2-YL)METHYL]BENZENE-1,3-DICARBOXAMIDE'>8HD</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=8HD:N~3~-{(2S,3R)-3-HYDROXY-4-[{[4-(HYDROXYMETHYL)PHENYL]SULFONYL}(2-METHYLPROPYL)AMINO]-1-PHENYLBUTAN-2-YL}-N~1~-METHYL-N~1~-[(4-METHYL-1,3-OXAZOL-2-YL)METHYL]BENZENE-1,3-DICARBOXAMIDE'>8HD</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5ult|5ult]], [[5uov|5uov]]</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5ult|5ult]], [[5uov|5uov]]</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">pol ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=11676 9HIV1])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5upz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5upz OCA], [http://pdbe.org/5upz PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5upz RCSB], [http://www.ebi.ac.uk/pdbsum/5upz PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5upz ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5upz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5upz OCA], [http://pdbe.org/5upz PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5upz RCSB], [http://www.ebi.ac.uk/pdbsum/5upz PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5upz ProSAT]</span></td></tr>
</table>
</table>

Revision as of 14:36, 6 November 2017

HIV-1 wild Type protease with GRL-0518A , an isophthalamide-derived P2-P3 ligand with the para-hydoxymethyl sulfonamide isostere as the P2' group

5upz, resolution 1.27Å

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