295d

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|PDB= 295d |SIZE=350|CAPTION= <scene name='initialview01'>295d</scene>, resolution 1.500&Aring;
|PDB= 295d |SIZE=350|CAPTION= <scene name='initialview01'>295d</scene>, resolution 1.500&Aring;
|SITE=
|SITE=
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|LIGAND=
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|LIGAND= <scene name='pdbligand=DA:2&#39;-DEOXYADENOSINE-5&#39;-MONOPHOSPHATE'>DA</scene>, <scene name='pdbligand=DC:2&#39;-DEOXYCYTIDINE-5&#39;-MONOPHOSPHATE'>DC</scene>, <scene name='pdbligand=DG:2&#39;-DEOXYGUANOSINE-5&#39;-MONOPHOSPHATE'>DG</scene>, <scene name='pdbligand=DT:THYMIDINE-5&#39;-MONOPHOSPHATE'>DT</scene>
|ACTIVITY=
|ACTIVITY=
|GENE=
|GENE=
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|DOMAIN=
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|RELATEDENTRY=
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|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=295d FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=295d OCA], [http://www.ebi.ac.uk/pdbsum/295d PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=295d RCSB]</span>
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[[Category: double helix]]
[[Category: double helix]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 15:43:48 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 31 01:46:02 2008''

Revision as of 22:46, 30 March 2008


PDB ID 295d

Drag the structure with the mouse to rotate
, resolution 1.500Å
Ligands: , , ,
Resources: FirstGlance, OCA, PDBsum, RCSB
Coordinates: save as pdb, mmCIF, xml



CRYSTAL AND SOLUTION STRUCTURES OF THE OLIGONUCLEOTIDE D(ATGCGCAT)2: A COMBINED X-RAY AND NMR STUDY


Overview

A combined crystal-structure determination and NMR analysis of the octanucleotide d(ATGCGCAT)2 is reported. The X-ray analysis shows that the structure is A-form duplex in crystal state. The NMR study shows that in solution this sequence is B-type. The conformational results from each technique are presented in detail. The implications of these findings in terms of conformational flexibility and ligand binding are discussed.

About this Structure

295D is a Protein complex structure of sequences from [1]. Full crystallographic information is available from OCA.

Reference

Crystal and solution structures of the oligonucleotide d(ATGCGCAT)2: a combined X-ray and NMR study., Clark GR, Brown DG, Sanderson MR, Chwalinski T, Neidle S, Veal JM, Jones RL, Wilson WD, Zon G, Garman E, et al., Nucleic Acids Res. 1990 Sep 25;18(18):5521-8. PMID:2216724

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