2a0x
From Proteopedia
(Difference between revisions)
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|PDB= 2a0x |SIZE=350|CAPTION= <scene name='initialview01'>2a0x</scene>, resolution 2.28Å | |PDB= 2a0x |SIZE=350|CAPTION= <scene name='initialview01'>2a0x</scene>, resolution 2.28Å | ||
|SITE= | |SITE= | ||
| - | |LIGAND= | + | |LIGAND= <scene name='pdbligand=DIH:3-HYDROXY-4-HYDROXYMETHYL-1-(4-OXO-4,4A,5,7A-TETRAHYDRO-3H-PYRROLO[3,2-D]PYRIMIDIN-7-YLMETHYL)-PYRROLIDINIUM'>DIH</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene> |
| - | |ACTIVITY= [http://en.wikipedia.org/wiki/Purine-nucleoside_phosphorylase Purine-nucleoside phosphorylase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.4.2.1 2.4.2.1] | + | |ACTIVITY= <span class='plainlinks'>[http://en.wikipedia.org/wiki/Purine-nucleoside_phosphorylase Purine-nucleoside phosphorylase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.4.2.1 2.4.2.1] </span> |
|GENE= NP, PNP ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens]) | |GENE= NP, PNP ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens]) | ||
| + | |DOMAIN= | ||
| + | |RELATEDENTRY=[[1a0w|1A0W]], [[2a0y|2A0Y]] | ||
| + | |RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2a0x FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2a0x OCA], [http://www.ebi.ac.uk/pdbsum/2a0x PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=2a0x RCSB]</span> | ||
}} | }} | ||
'''Structure of human purine nucleoside phosphorylase H257F mutant''' | '''Structure of human purine nucleoside phosphorylase H257F mutant''' | ||
| - | |||
| - | ==Disease== | ||
| - | Known diseases associated with this structure: Neutral lipid storage disease with myopathy OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=609059 609059]], Nucleoside phosphorylase deficiency, immunodeficiency due to OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=164050 164050]] | ||
==About this Structure== | ==About this Structure== | ||
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[[Category: Schramm, V L.]] | [[Category: Schramm, V L.]] | ||
[[Category: Shi, W.]] | [[Category: Shi, W.]] | ||
| - | [[Category: DIH]] | ||
| - | [[Category: SO4]] | ||
[[Category: mutant]] | [[Category: mutant]] | ||
[[Category: purine nucleoside phosphorylase]] | [[Category: purine nucleoside phosphorylase]] | ||
[[Category: transition state inhibitor]] | [[Category: transition state inhibitor]] | ||
| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 31 01:46:21 2008'' |
Revision as of 22:46, 30 March 2008
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| , resolution 2.28Å | |||||||
|---|---|---|---|---|---|---|---|
| Ligands: | , | ||||||
| Gene: | NP, PNP (Homo sapiens) | ||||||
| Activity: | Purine-nucleoside phosphorylase, with EC number 2.4.2.1 | ||||||
| Related: | 1A0W, 2A0Y
| ||||||
| Resources: | FirstGlance, OCA, PDBsum, RCSB | ||||||
| Coordinates: | save as pdb, mmCIF, xml | ||||||
Structure of human purine nucleoside phosphorylase H257F mutant
About this Structure
2A0X is a Single protein structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.
Page seeded by OCA on Mon Mar 31 01:46:21 2008
