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5ob5
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==fAb complex with GroBeta. AbVance: increasing our knowledge of antibody structural space to enable faster and better decision-making in antibody drug discovery.== | |
| - | + | <StructureSection load='5ob5' size='340' side='right' caption='[[5ob5]], [[Resolution|resolution]] 1.65Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[5ob5]] is a 3 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5OB5 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5OB5 FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5ob5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5ob5 OCA], [http://pdbe.org/5ob5 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5ob5 RCSB], [http://www.ebi.ac.uk/pdbsum/5ob5 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5ob5 ProSAT]</span></td></tr> |
| + | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/CXCL2_HUMAN CXCL2_HUMAN]] Produced by activated monocytes and neutrophils and expressed at sites of inflammation. Hematoregulatory chemokine, which, in vitro, suppresses hematopoietic progenitor cell proliferation. GRO-beta(5-73) shows a highly enhanced hematopoietic activity.<ref>PMID:10725737</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Convery, M A]] | ||
| + | [[Category: Ward, P]] | ||
[[Category: Zhao, B]] | [[Category: Zhao, B]] | ||
| - | [[Category: | + | [[Category: Abvance project]] |
| - | [[Category: | + | [[Category: Fab complex]] |
| + | [[Category: Immune system]] | ||
| + | [[Category: Pistoia alliance]] | ||
Revision as of 07:48, 8 November 2017
fAb complex with GroBeta. AbVance: increasing our knowledge of antibody structural space to enable faster and better decision-making in antibody drug discovery.
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