Thioredoxin

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Line 40: Line 40:
**[[2h6x]], [[2trx]], [[1srx]] – EcTrx – ''Escherichia coli''<br />
**[[2h6x]], [[2trx]], [[1srx]] – EcTrx – ''Escherichia coli''<br />
**[[1xoa]], [[1xob]] – EcTrx - NMR<br />
**[[1xoa]], [[1xob]] – EcTrx - NMR<br />
-
**[[2tir]], [[4hua]], [[4hu9]], [[4hu7]] - EcTrx (mutant) <br />
+
**[[2tir]], [[4hua]], [[4hu9]], [[4hu7]], [[5hr2]], [[5hr3]], [[5hr0]] - EcTrx (mutant) <br />
**[[1m7t]] – hTrx/EcTrx chimera - NMR<br />
**[[1m7t]] – hTrx/EcTrx chimera - NMR<br />
**[[3emx]] – Trx – ''Aeropyrum pernix''<br />
**[[3emx]] – Trx – ''Aeropyrum pernix''<br />
Line 65: Line 65:
**[[2xbq]], [[2xc2]] – SmTrx (mutant)<br />
**[[2xbq]], [[2xc2]] – SmTrx (mutant)<br />
**[[4i8b]] - Trx – ''Schistosoma japonicum''<br />
**[[4i8b]] - Trx – ''Schistosoma japonicum''<br />
-
**[[3zzx]], [[4aj8]], [[4aj7]], [[4aj6]], [[4v2l]], [[4v2m]], [[4v2n]] – Trx – ''Litopenaeus vannamei''<br />
+
**[[3zzx]], [[4aj8]], [[4aj7]], [[4aj6]], [[4v2l]], [[4v2m]], [[4v2n]] – LvTrx – ''Litopenaeus vannamei''<br />
 +
**[[5hr0]] - LvTrx (mutant) <br />
**[[4fyu]] – Trx – ''Wuchereria bancrofti''<br />
**[[4fyu]] – Trx – ''Wuchereria bancrofti''<br />
**[[4knd]] – Trx – ''Anaeromyxobacter dehalogenans''<br />
**[[4knd]] – Trx – ''Anaeromyxobacter dehalogenans''<br />
Line 78: Line 79:
**[[4cw9]] - Trx (mutant) – ''Entamoeba histolytica''<br />
**[[4cw9]] - Trx (mutant) – ''Entamoeba histolytica''<br />
**[[4wxt]] - Trx – ''Mycobacterium avium''<br />
**[[4wxt]] - Trx – ''Mycobacterium avium''<br />
 +
**[[5jy5]] - Trx – ''Cryptococcus neoformans''<br />
 +
**[[5ap5]] - Trx – ''Mycobacterium thermoresistibile'' - NMR<br />
 +
**[[5vo7]] - Trx – ''Mycobacterium smegmatis'' - NMR<br />
**[[5dbq]] - Trx – velvetbean caterpillar<br />
**[[5dbq]] - Trx – velvetbean caterpillar<br />
Line 97: Line 101:
**[[2n5a]] – yTrx-1 (mutant) reduced<br />
**[[2n5a]] – yTrx-1 (mutant) reduced<br />
**[[2n5b]] – yTrx-1 (mutant) oxidized<br />
**[[2n5b]] – yTrx-1 (mutant) oxidized<br />
-
**[[3dyr]], [[2h6y]], [[2h6z]], [[2h70]], [[2h71]], [[2h72]], [[2h73]], [[2h74]], [[2h75]], [[2h76]], [[2fch]], [[2fd3]], [[1keb]], [[2eio]], [[2eiq]], [[2eir]], [[1zcp]], [[1zzy]], [[1txx]], [[1tho]], [[4x43]] – EcTrx-1 (mutant) <br />
+
**[[3dyr]], [[2h6y]], [[2h6z]], [[2h70]], [[2h71]], [[2h72]], [[2h73]], [[2h74]], [[2h75]], [[2h76]], [[2fch]], [[2fd3]], [[1keb]], [[2eio]], [[2eiq]], [[2eir]], [[1zcp]], [[1zzy]], [[1txx]], [[1tho]], [[4x43]], [[5hr1]] – EcTrx-1 (mutant) <br />
**[[1f6m]] – EcTrx-1+Trx reductase+AADP+<br />
**[[1f6m]] – EcTrx-1+Trx reductase+AADP+<br />
**[[5e4w]] - EcTrx-1 + signal recognition particle + Albino3<br />
**[[5e4w]] - EcTrx-1 + signal recognition particle + Albino3<br />
 +
**[[5ikn]] - EcTrx-1 + T7DNA-directed DNA polymerase + T7DNA primase<br />
**[[2o8v]] - EcTrx-1 (mutant) + PAPS reductase<br />
**[[2o8v]] - EcTrx-1 (mutant) + PAPS reductase<br />
**[[2ajq]] – EpTrx-1 (mutant)+DNA primer+DNA template+DNA polymerase – Enterobacteria phage T7<br />
**[[2ajq]] – EpTrx-1 (mutant)+DNA primer+DNA template+DNA polymerase – Enterobacteria phage T7<br />

Revision as of 09:10, 8 November 2017

Human thioredoxin (PDB entry 1ert)

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3D Structures of Thioredoxin

Updated on 08-November-2017

References

  1. Gleason FK, Holmgren A. Thioredoxin and related proteins in procaryotes. FEMS Microbiol Rev. 1988 Dec;4(4):271-97. PMID:3152490
  2. Sumida Y, Nakashima T, Yoh T, Furutani M, Hirohama A, Kakisaka Y, Nakajima Y, Ishikawa H, Mitsuyoshi H, Okanoue T, Kashima K, Nakamura H, Yodoi J. Serum thioredoxin levels as a predictor of steatohepatitis in patients with nonalcoholic fatty liver disease. J Hepatol. 2003 Jan;38(1):32-8. PMID:12480557
  3. Burke-Gaffney A, Callister ME, Nakamura H. Thioredoxin: friend or foe in human disease? Trends Pharmacol Sci. 2005 Aug;26(8):398-404. PMID:15990177 doi:http://dx.doi.org/10.1016/j.tips.2005.06.005
  4. Weichsel A, Gasdaska JR, Powis G, Montfort WR. Crystal structures of reduced, oxidized, and mutated human thioredoxins: evidence for a regulatory homodimer. Structure. 1996 Jun 15;4(6):735-51. PMID:8805557
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