5vx1
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Bak L100A== | |
| - | + | <StructureSection load='5vx1' size='340' side='right' caption='[[5vx1]], [[Resolution|resolution]] 1.22Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[5vx1]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5VX1 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5VX1 FirstGlance]. <br> | |
| - | + | </td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5vwv|5vwv]], [[5vww|5vww]], [[5vwx|5vwx]], [[5vwy|5vwy]], [[5vwz|5vwz]], [[5vx0|5vx0]], [[5vx2|5vx2]], [[5vx3|5vx3]]</td></tr> | |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5vx1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5vx1 OCA], [http://pdbe.org/5vx1 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5vx1 RCSB], [http://www.ebi.ac.uk/pdbsum/5vx1 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5vx1 ProSAT]</span></td></tr> |
| + | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/BAK_HUMAN BAK_HUMAN]] In the presence of an appropriate stimulus, accelerates programmed cell death by binding to, and antagonizing the anti-apoptotic action of BCL2 or its adenovirus homolog E1B 19k protein. Low micromolar levels of zinc ions inhibit the promotion of apoptosis.<ref>PMID:8521816</ref> <ref>PMID:17157251</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Brouwer, J M]] | ||
| + | [[Category: Colman, P M]] | ||
| + | [[Category: Czabotar, P E]] | ||
| + | [[Category: Apoptosis]] | ||
| + | [[Category: Bcl-2 family]] | ||
| + | [[Category: Mutant]] | ||
Revision as of 07:34, 15 November 2017
Bak L100A
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