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5wdm
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==An ultra-stable single-chain insulin analog resists thermal inactivation and exhibits biological signaling duration equivalent to the native protein== | |
| - | + | <StructureSection load='5wdm' size='340' side='right' caption='[[5wdm]], [[Resolution|resolution]] 2.80Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[5wdm]] is a 6 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5WDM OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5WDM FirstGlance]. <br> | |
| - | + | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5wdm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5wdm OCA], [http://pdbe.org/5wdm PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5wdm RCSB], [http://www.ebi.ac.uk/pdbsum/5wdm PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5wdm ProSAT]</span></td></tr> | |
| - | [[Category: | + | </table> |
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/A6XGL2_HUMAN A6XGL2_HUMAN]] Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver (By similarity).[SAAS:SAAS022353_004_028339] | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Aldabbagh, K]] | ||
| + | [[Category: Peng, Y]] | ||
| + | [[Category: Yee, V C]] | ||
| + | [[Category: Designed insulin]] | ||
| + | [[Category: Hexamer]] | ||
| + | [[Category: Hormone]] | ||
| + | [[Category: Single chain]] | ||
Revision as of 07:35, 15 November 2017
An ultra-stable single-chain insulin analog resists thermal inactivation and exhibits biological signaling duration equivalent to the native protein
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Categories: Aldabbagh, K | Peng, Y | Yee, V C | Designed insulin | Hexamer | Hormone | Single chain
