5ws4
From Proteopedia
(Difference between revisions)
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of tripartite-type ABC transporter MacB from Acinetobacter baumannii== | |
| - | + | <StructureSection load='5ws4' size='340' side='right' caption='[[5ws4]], [[Resolution|resolution]] 3.40Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[5ws4]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5WS4 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5WS4 FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=AT4:5-O-[(R)-HYDROXY(THIOPHOSPHONOOXY)PHOSPHORYL]ADENOSINE'>AT4</scene></td></tr> | |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5ws4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5ws4 OCA], [http://pdbe.org/5ws4 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5ws4 RCSB], [http://www.ebi.ac.uk/pdbsum/5ws4 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5ws4 ProSAT]</span></td></tr> |
| + | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/A0A0D8G707_ACIBA A0A0D8G707_ACIBA]] Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides.[HAMAP-Rule:MF_01720] | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Murakami, S]] | ||
| + | [[Category: Okada, U]] | ||
| + | [[Category: Yamashita, E]] | ||
| + | [[Category: Abc transporter]] | ||
| + | [[Category: Drug exporter]] | ||
| + | [[Category: Membrane protein]] | ||
| + | [[Category: Multi-drug efflux transporter]] | ||
Revision as of 07:36, 15 November 2017
Crystal structure of tripartite-type ABC transporter MacB from Acinetobacter baumannii
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