5wy6
From Proteopedia
(Difference between revisions)
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of AtNUDX1 (E56A)== | |
| - | + | <StructureSection load='5wy6' size='340' side='right' caption='[[5wy6]], [[Resolution|resolution]] 1.78Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[5wy6]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5WY6 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5WY6 FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5wy6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5wy6 OCA], [http://pdbe.org/5wy6 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5wy6 RCSB], [http://www.ebi.ac.uk/pdbsum/5wy6 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5wy6 ProSAT]</span></td></tr> |
| + | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/NUDT1_ARATH NUDT1_ARATH]] Mediates the hydrolysis of some nucleoside diphosphate derivatives. Its substrate specificity is unclear. In vitro, it can use NTP, dNTP, 8-oxo-GTP, 8-oxo-dGTP, dGTP, dATP, dTTP or dihydroneopterin triphosphate (DHNTP) as substrate. Has some NADH pyrophosphatase activity in vitro; however, such activity may not be relevant in vivo due to the high concentration of manganese used during the experiments. Plays an important role in protection against oxidative DNA and RNA damage by removing oxidatively damaged form of guanine.<ref>PMID:15611104</ref> <ref>PMID:15878881</ref> <ref>PMID:17804481</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Guan, Z]] | ||
| + | [[Category: Liu, J]] | ||
| + | [[Category: Yan, L]] | ||
| + | [[Category: Yin, P]] | ||
| + | [[Category: Zou, T]] | ||
| + | [[Category: Apo]] | ||
| + | [[Category: E56a mutant]] | ||
| + | [[Category: Hydrolase]] | ||
| + | [[Category: Nudx1]] | ||
Revision as of 07:38, 15 November 2017
Crystal structure of AtNUDX1 (E56A)
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Categories: Guan, Z | Liu, J | Yan, L | Yin, P | Zou, T | Apo | E56a mutant | Hydrolase | Nudx1
