5yl4
From Proteopedia
(Difference between revisions)
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| - | '''Unreleased structure''' | ||
| - | + | ==CRYSTAL STRUCTURE OF T2R-TTL-8WR COMPLEX== | |
| - | + | <StructureSection load='5yl4' size='340' side='right' caption='[[5yl4]], [[Resolution|resolution]] 2.64Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[5yl4]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/ ] and [http://en.wikipedia.org/wiki/Sus_barbatus Sus barbatus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5YL4 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5YL4 FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=8WR:(3Z,6Z)-3-[(4-tert-butyl-1H-imidazol-5-yl)methylidene]-6-[[3-(phenylcarbonyl)phenyl]methylidene]piperazine-2,5-dione'>8WR</scene>, <scene name='pdbligand=ACP:PHOSPHOMETHYLPHOSPHONIC+ACID+ADENYLATE+ESTER'>ACP</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=GDP:GUANOSINE-5-DIPHOSPHATE'>GDP</scene>, <scene name='pdbligand=GTP:GUANOSINE-5-TRIPHOSPHATE'>GTP</scene>, <scene name='pdbligand=MES:2-(N-MORPHOLINO)-ETHANESULFONIC+ACID'>MES</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr> | |
| - | [[Category: | + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5xi5|5xi5]], [[5xi7|5xi7]], [[5xhc|5xhc]]</td></tr> |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5yl4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5yl4 OCA], [http://pdbe.org/5yl4 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5yl4 RCSB], [http://www.ebi.ac.uk/pdbsum/5yl4 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5yl4 ProSAT]</span></td></tr> |
| - | [[Category: Hou, Y | + | </table> |
| - | [[Category: Li, W | + | == Function == |
| - | [[Category: | + | [[http://www.uniprot.org/uniprot/A0A0R4I993_SUSBA A0A0R4I993_SUSBA]] Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.[RuleBase:RU000352][SAAS:SAAS00824325] [[http://www.uniprot.org/uniprot/STMN4_RAT STMN4_RAT]] Exhibits microtubule-destabilizing activity.<ref>PMID:15039434</ref> <ref>PMID:12111843</ref> <ref>PMID:15014504</ref> [[http://www.uniprot.org/uniprot/A0A0R4I995_SUSBA A0A0R4I995_SUSBA]] Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.[RuleBase:RU000352][SAAS:SAAS00103861] |
| - | [[Category: | + | == References == |
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Sus barbatus]] | ||
| + | [[Category: Chu, Y Y]] | ||
| + | [[Category: Fu, Z Y]] | ||
| + | [[Category: Hou, Y W]] | ||
| + | [[Category: Ji, C P]] | ||
| + | [[Category: Li, W B]] | ||
| + | [[Category: Colchicine]] | ||
| + | [[Category: Diketopiperazine]] | ||
| + | [[Category: Microtubule]] | ||
| + | [[Category: Structural protein]] | ||
| + | [[Category: Tubulin]] | ||
Revision as of 07:39, 15 November 2017
CRYSTAL STRUCTURE OF T2R-TTL-8WR COMPLEX
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Categories: Sus barbatus | Chu, Y Y | Fu, Z Y | Hou, Y W | Ji, C P | Li, W B | Colchicine | Diketopiperazine | Microtubule | Structural protein | Tubulin
