4fss
From Proteopedia
(Difference between revisions)
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==Crystal structure of a RAS p21 protein activator (RASA1) from Homo sapiens at 2.25 A resolution== | ==Crystal structure of a RAS p21 protein activator (RASA1) from Homo sapiens at 2.25 A resolution== | ||
<StructureSection load='4fss' size='340' side='right' caption='[[4fss]], [[Resolution|resolution]] 2.25Å' scene=''> | <StructureSection load='4fss' size='340' side='right' caption='[[4fss]], [[Resolution|resolution]] 2.25Å' scene=''> | ||
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<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr> | <tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr> | ||
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">BC033015, RASA, RASA1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr> | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">BC033015, RASA, RASA1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr> | ||
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4fss FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4fss OCA], [http://pdbe.org/4fss PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4fss RCSB], [http://www.ebi.ac.uk/pdbsum/4fss PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4fss FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4fss OCA], [http://pdbe.org/4fss PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4fss RCSB], [http://www.ebi.ac.uk/pdbsum/4fss PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4fss ProSAT]</span></td></tr> |
</table> | </table> | ||
== Disease == | == Disease == | ||
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== Function == | == Function == | ||
[[http://www.uniprot.org/uniprot/RASA1_HUMAN RASA1_HUMAN]] Inhibitory regulator of the Ras-cyclic AMP pathway. Stimulates the GTPase of normal but not oncogenic Ras p21; this stimulation may be further increased in the presence of NCK1.<ref>PMID:8360177</ref> <ref>PMID:11389730</ref> | [[http://www.uniprot.org/uniprot/RASA1_HUMAN RASA1_HUMAN]] Inhibitory regulator of the Ras-cyclic AMP pathway. Stimulates the GTPase of normal but not oncogenic Ras p21; this stimulation may be further increased in the presence of NCK1.<ref>PMID:8360177</ref> <ref>PMID:11389730</ref> | ||
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| - | ==See Also== | ||
| - | *[[Ras GTPase activating protein|Ras GTPase activating protein]] | ||
== References == | == References == | ||
<references/> | <references/> | ||
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[[Category: Gtpase activating protein]] | [[Category: Gtpase activating protein]] | ||
[[Category: Jcsg]] | [[Category: Jcsg]] | ||
| + | [[Category: Partnership for t-cell biology]] | ||
[[Category: PSI, Protein structure initiative]] | [[Category: PSI, Protein structure initiative]] | ||
[[Category: Psi-biology]] | [[Category: Psi-biology]] | ||
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[[Category: Sh3 domain]] | [[Category: Sh3 domain]] | ||
[[Category: Signaling protein]] | [[Category: Signaling protein]] | ||
| + | [[Category: Tcell]] | ||
Revision as of 08:20, 15 November 2017
Crystal structure of a RAS p21 protein activator (RASA1) from Homo sapiens at 2.25 A resolution
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