This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.


Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


5knp

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Line 1: Line 1:
-
'''Unreleased structure'''
 
-
The entry 5knp is ON HOLD until Paper Publication
+
==Crystal structure of Mycobacterium tuberculosis hypoxanthine guanine phosphoribosyltransferase in complex with [3S,4R]-(4-(Hypoxanthin-9-yl)pyrrolidin-3-yl)-oxymethanephosphonic acid==
-
 
+
<StructureSection load='5knp' size='340' side='right' caption='[[5knp]], [[Resolution|resolution]] 2.45&Aring;' scene=''>
-
Authors: Eng, W.S., Rejman, D., Keough, D.T., Guddat, L.W.
+
== Structural highlights ==
-
 
+
<table><tr><td colspan='2'>[[5knp]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Myctu Myctu]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5KNP OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5KNP FirstGlance]. <br>
-
Description: Crystal structure of Mycobacterium tuberculosis hypoxanthine guanine phosphoribosyltransferase in complex with [3S,4R]-(4-(Hypoxanthin-9-yl)pyrrolidin-3-yl)-oxymethanephosphonic acid
+
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=6W7:[(3~{S},4~{R})-4-(6-oxidanylidene-1~{H}-purin-9-yl)pyrrolidin-3-yl]oxymethylphosphonic+acid'>6W7</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=POP:PYROPHOSPHATE+2-'>POP</scene></td></tr>
-
[[Category: Unreleased Structures]]
+
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5knq|5knq]], [[5kny|5kny]], [[5knr|5knr]], [[5kns|5kns]], [[5knv|5knv]], [[5knu|5knu]], [[5knt|5knt]], [[5knx|5knx]]</td></tr>
-
[[Category: Eng, W.S]]
+
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">hpt, hprT, Rv3624c, MTCY15C10.28 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=83332 MYCTU])</td></tr>
 +
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Hypoxanthine_phosphoribosyltransferase Hypoxanthine phosphoribosyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.4.2.8 2.4.2.8] </span></td></tr>
 +
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5knp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5knp OCA], [http://pdbe.org/5knp PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5knp RCSB], [http://www.ebi.ac.uk/pdbsum/5knp PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5knp ProSAT]</span></td></tr>
 +
</table>
 +
__TOC__
 +
</StructureSection>
 +
[[Category: Hypoxanthine phosphoribosyltransferase]]
 +
[[Category: Myctu]]
 +
[[Category: Eng, W S]]
 +
[[Category: Guddat, L W]]
 +
[[Category: Keough, D T]]
[[Category: Rejman, D]]
[[Category: Rejman, D]]
-
[[Category: Keough, D.T]]
+
[[Category: Complex]]
-
[[Category: Guddat, L.W]]
+
[[Category: Inhibitor]]
 +
[[Category: Nucleoside phosphonate]]
 +
[[Category: Phosphoribosyltransferase]]
 +
[[Category: Transferase-inhibitor complex]]

Revision as of 14:11, 15 November 2017

Crystal structure of Mycobacterium tuberculosis hypoxanthine guanine phosphoribosyltransferase in complex with [3S,4R]-(4-(Hypoxanthin-9-yl)pyrrolidin-3-yl)-oxymethanephosphonic acid

5knp, resolution 2.45Å

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Personal tools