We apologize for Proteopedia being slow to respond. For the past two years, a new implementation of Proteopedia has been being built. Soon, it will replace this 18-year old system. All existing content will be moved to the new system at a date that will be announced here.
5ltd
From Proteopedia
(Difference between revisions)
m (Protected "5ltd" [edit=sysop:move=sysop]) |
|||
| Line 1: | Line 1: | ||
| - | '''Unreleased structure''' | ||
| - | + | ==Phosphate-bound Pichia angusta Atg18== | |
| - | + | <StructureSection load='5ltd' size='340' side='right' caption='[[5ltd]], [[Resolution|resolution]] 2.50Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[5ltd]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Cbs_7073 Cbs 7073]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5LTD OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5LTD FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr> | |
| - | [[Category: | + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">ATG18 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=870730 CBS 7073])</td></tr> |
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5ltd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5ltd OCA], [http://pdbe.org/5ltd PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5ltd RCSB], [http://www.ebi.ac.uk/pdbsum/5ltd PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5ltd ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/ATG18_PICAN ATG18_PICAN]] The PI(3,5)P2 regulatory complex regulates both the synthesis and turnover of phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2). Necessary for proper vacuole morphology. Plays an important role in osmotically-induced vacuole fragmentation. Required for cytoplasm to vacuole transport (Cvt) vesicle formation, pexophagy and starvation-induced autophagy. Involved in correct ATG9 trafficking to the pre-autophagosomal structure. Might also be involved in premeiotic DNA replication (By similarity). | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Cbs 7073]] | ||
| + | [[Category: Kuhnel, K]] | ||
[[Category: Scacioc, A]] | [[Category: Scacioc, A]] | ||
| - | [[Category: | + | [[Category: Lipid binding protein]] |
| + | [[Category: Membrane bound protein]] | ||
Revision as of 14:15, 15 November 2017
Phosphate-bound Pichia angusta Atg18
| |||||||||||
