5iez

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<StructureSection load='5iez' size='340' side='right' caption='[[5iez]], [[Resolution|resolution]] 2.60&Aring;' scene=''>
<StructureSection load='5iez' size='340' side='right' caption='[[5iez]], [[Resolution|resolution]] 2.60&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[5iez]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5IEZ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5IEZ FirstGlance]. <br>
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<table><tr><td colspan='2'>[[5iez]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5IEZ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5IEZ FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=6AL:3-({6-CHLORO-3-[3-(4-CHLORO-3,5-DIMETHYLPHENOXY)PROPYL]-7-(1,3,5-TRIMETHYL-1H-PYRAZOL-4-YL)-1H-INDOLE-2-CARBONYL}AMINO)BENZOIC+ACID'>6AL</scene></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=6AL:3-({6-CHLORO-3-[3-(4-CHLORO-3,5-DIMETHYLPHENOXY)PROPYL]-7-(1,3,5-TRIMETHYL-1H-PYRAZOL-4-YL)-1H-INDOLE-2-CARBONYL}AMINO)BENZOIC+ACID'>6AL</scene></td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5if4|5if4]]</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5if4|5if4]]</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">MCL1, BCL2L3 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5iez FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5iez OCA], [http://pdbe.org/5iez PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5iez RCSB], [http://www.ebi.ac.uk/pdbsum/5iez PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5iez ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5iez FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5iez OCA], [http://pdbe.org/5iez PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5iez RCSB], [http://www.ebi.ac.uk/pdbsum/5iez PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5iez ProSAT]</span></td></tr>
</table>
</table>
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Human]]
[[Category: Zhao, B]]
[[Category: Zhao, B]]
[[Category: Apoptosis]]
[[Category: Apoptosis]]

Revision as of 17:37, 15 November 2017

Discovery of Potent Myeloid Cell Leukemia-1 (Mcl-1) inhibitors using Structure-Based Design

5iez, resolution 2.60Å

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