This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
5us1
From Proteopedia
(Difference between revisions)
| Line 3: | Line 3: | ||
<StructureSection load='5us1' size='340' side='right' caption='[[5us1]], [[Resolution|resolution]] 2.48Å' scene=''> | <StructureSection load='5us1' size='340' side='right' caption='[[5us1]], [[Resolution|resolution]] 2.48Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[5us1]] is a 12 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5US1 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5US1 FirstGlance]. <br> | + | <table><tr><td colspan='2'>[[5us1]] is a 12 chain structure with sequence from [http://en.wikipedia.org/wiki/"proteus_stuartii"_buttiaux_et_al._1954 "proteus stuartii" buttiaux et al. 1954]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5US1 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5US1 FirstGlance]. <br> |
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=8MM:(1R,2S,3S,4R,6S)-4,6-DIAMINO-3-{[3-DEOXY-4-C-METHYL-3-(METHYLAMINO)-BETA-L-ARABINOPYRANOSYL]OXY}-2-HYDROXYCYCLOHEXYL+2-(ACETYLAMINO)-6-AMINO-2,3,4,6-TETRADEOXY-ALPHA-D-ERYTHRO-HEXOPYRANOSIDE'>8MM</scene>, <scene name='pdbligand=ACO:ACETYL+COENZYME+*A'>ACO</scene>, <scene name='pdbligand=COA:COENZYME+A'>COA</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=TAR:D(-)-TARTARIC+ACID'>TAR</scene></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=8MM:(1R,2S,3S,4R,6S)-4,6-DIAMINO-3-{[3-DEOXY-4-C-METHYL-3-(METHYLAMINO)-BETA-L-ARABINOPYRANOSYL]OXY}-2-HYDROXYCYCLOHEXYL+2-(ACETYLAMINO)-6-AMINO-2,3,4,6-TETRADEOXY-ALPHA-D-ERYTHRO-HEXOPYRANOSIDE'>8MM</scene>, <scene name='pdbligand=ACO:ACETYL+COENZYME+*A'>ACO</scene>, <scene name='pdbligand=COA:COENZYME+A'>COA</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=TAR:D(-)-TARTARIC+ACID'>TAR</scene></td></tr> | ||
| + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">aac ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=588 "Proteus stuartii" Buttiaux et al. 1954])</td></tr> | ||
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Gentamicin_2'-N-acetyltransferase Gentamicin 2'-N-acetyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.3.1.59 2.3.1.59] </span></td></tr> | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Gentamicin_2'-N-acetyltransferase Gentamicin 2'-N-acetyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.3.1.59 2.3.1.59] </span></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5us1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5us1 OCA], [http://pdbe.org/5us1 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5us1 RCSB], [http://www.ebi.ac.uk/pdbsum/5us1 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5us1 ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5us1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5us1 OCA], [http://pdbe.org/5us1 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5us1 RCSB], [http://www.ebi.ac.uk/pdbsum/5us1 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5us1 ProSAT]</span></td></tr> | ||
| Line 10: | Line 11: | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| + | [[Category: Proteus stuartii buttiaux et al. 1954]] | ||
[[Category: Gentamicin 2'-N-acetyltransferase]] | [[Category: Gentamicin 2'-N-acetyltransferase]] | ||
[[Category: Anderson, W F]] | [[Category: Anderson, W F]] | ||
Revision as of 19:46, 15 November 2017
Crystal structure of aminoglycoside acetyltransferase AAC(2')-Ia in complex with N2'-acetylgentamicin C1A and coenzyme A
| |||||||||||
Categories: Proteus stuartii buttiaux et al. 1954 | Gentamicin 2'-N-acetyltransferase | Anderson, W F | Structural genomic | Evdokimova, E | Savchenko, A | Stogios, P J | Wawrzak, Z | Xu, Z | Acetylcoenzyme a antibiotic resistance | Acetyltransferase | Aminoglycoside | Coenzyme some | Csgid | Gcn5-n-acetyltransferase | Gentamicin | Gnat | National institute of allergy and infectious disease | Niaid | Transferase
