5fxt
From Proteopedia
(Difference between revisions)
| Line 1: | Line 1: | ||
| - | '''Unreleased structure''' | ||
| - | + | ==Crystal Structure of Helicobacter pylori beta clamp in complex with Carprofen== | |
| - | + | <StructureSection load='5fxt' size='340' side='right' caption='[[5fxt]], [[Resolution|resolution]] 1.97Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[5fxt]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Campylobacter_pylori Campylobacter pylori]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5FXT OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5FXT FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=0LA:(2S)-2-(6-CHLORO-9H-CARBAZOL-2-YL)PROPANOIC+ACID'>0LA</scene></td></tr> | |
| - | [[Category: | + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/DNA-directed_DNA_polymerase DNA-directed DNA polymerase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.7.7 2.7.7.7] </span></td></tr> |
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5fxt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5fxt OCA], [http://pdbe.org/5fxt PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5fxt RCSB], [http://www.ebi.ac.uk/pdbsum/5fxt PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5fxt ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/DPO3B_HELPY DPO3B_HELPY]] DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP-independent) along duplex DNA (By similarity). | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Campylobacter pylori]] | ||
| + | [[Category: DNA-directed DNA polymerase]] | ||
| + | [[Category: Gourinath, S]] | ||
[[Category: Pandey, P]] | [[Category: Pandey, P]] | ||
| - | [[Category: | + | [[Category: Dna clamp]] |
| + | [[Category: Sliding clamp]] | ||
| + | [[Category: Transferase]] | ||
Revision as of 23:44, 15 November 2017
Crystal Structure of Helicobacter pylori beta clamp in complex with Carprofen
| |||||||||||
