2fyp

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==GRP94 in complex with the novel HSP90 Inhibitor Radester amine==
==GRP94 in complex with the novel HSP90 Inhibitor Radester amine==
<StructureSection load='2fyp' size='340' side='right' caption='[[2fyp]], [[Resolution|resolution]] 1.95&Aring;' scene=''>
<StructureSection load='2fyp' size='340' side='right' caption='[[2fyp]], [[Resolution|resolution]] 1.95&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2fyp]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Canfa Canfa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2FYP OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2FYP FirstGlance]. <br>
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<table><tr><td colspan='2'>[[2fyp]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Canlf Canlf]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2FYP OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2FYP FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=1PE:PENTAETHYLENE+GLYCOL'>1PE</scene>, <scene name='pdbligand=PG4:TETRAETHYLENE+GLYCOL'>PG4</scene>, <scene name='pdbligand=RDE:2-(3-AMINO-2,5,6-TRIMETHOXYPHENYL)ETHYL+5-CHLORO-2,4-DIHYDROXYBENZOATE'>RDE</scene></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=1PE:PENTAETHYLENE+GLYCOL'>1PE</scene>, <scene name='pdbligand=PG4:TETRAETHYLENE+GLYCOL'>PG4</scene>, <scene name='pdbligand=RDE:2-(3-AMINO-2,5,6-TRIMETHOXYPHENYL)ETHYL+5-CHLORO-2,4-DIHYDROXYBENZOATE'>RDE</scene></td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1zwh|1zwh]], [[2fxs|2fxs]], [[1qy8|1qy8]], [[1u0z|1u0z]], [[2exl|2exl]], [[1yet|1yet]], [[1bgq|1bgq]], [[1osf|1osf]]</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1zwh|1zwh]], [[2fxs|2fxs]], [[1qy8|1qy8]], [[1u0z|1u0z]], [[2exl|2exl]], [[1yet|1yet]], [[1bgq|1bgq]], [[1osf|1osf]]</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">TRA1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9615 CANFA])</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">TRA1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9615 CANLF])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2fyp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2fyp OCA], [http://pdbe.org/2fyp PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2fyp RCSB], [http://www.ebi.ac.uk/pdbsum/2fyp PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2fyp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2fyp OCA], [http://pdbe.org/2fyp PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2fyp RCSB], [http://www.ebi.ac.uk/pdbsum/2fyp PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2fyp ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
</jmolCheckbox>
</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2fyp ConSurf].
<div style="clear:both"></div>
<div style="clear:both"></div>
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==See Also==
 
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*[[Endoplasmin|Endoplasmin]]
 
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Canfa]]
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[[Category: Canlf]]
[[Category: Gewirth, D T]]
[[Category: Gewirth, D T]]
[[Category: Immormino, R M]]
[[Category: Immormino, R M]]

Revision as of 02:09, 16 November 2017

GRP94 in complex with the novel HSP90 Inhibitor Radester amine

2fyp, resolution 1.95Å

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