2b1z
From Proteopedia
(Difference between revisions)
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|PDB= 2b1z |SIZE=350|CAPTION= <scene name='initialview01'>2b1z</scene>, resolution 1.78Å | |PDB= 2b1z |SIZE=350|CAPTION= <scene name='initialview01'>2b1z</scene>, resolution 1.78Å | ||
|SITE= | |SITE= | ||
- | |LIGAND= <scene name='pdbligand=17M:17-METHYL-17-ALPHA-DIHYDROEQUILENIN'>17M</scene> | + | |LIGAND= <scene name='pdbligand=17M:17-METHYL-17-ALPHA-DIHYDROEQUILENIN'>17M</scene>, <scene name='pdbligand=CME:S,S-(2-HYDROXYETHYL)THIOCYSTEINE'>CME</scene> |
|ACTIVITY= | |ACTIVITY= | ||
|GENE= ESR1, ESR, NR3A1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens]) | |GENE= ESR1, ESR, NR3A1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens]) | ||
+ | |DOMAIN= | ||
+ | |RELATEDENTRY=[[2b1v|2B1V]], [[2b23|2B23]] | ||
+ | |RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2b1z FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2b1z OCA], [http://www.ebi.ac.uk/pdbsum/2b1z PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=2b1z RCSB]</span> | ||
}} | }} | ||
'''Human estrogen receptor alpha ligand-binding domain in complex with 17methyl-17alpha-dihydroequilenin and a glucoc interacting protein 1 NR box II peptide''' | '''Human estrogen receptor alpha ligand-binding domain in complex with 17methyl-17alpha-dihydroequilenin and a glucoc interacting protein 1 NR box II peptide''' | ||
- | |||
- | ==Disease== | ||
- | Known diseases associated with this structure: Atherosclerosis, susceptibility to OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=133430 133430]], Breast cancer OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=133430 133430]], Estrogen resistance OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=133430 133430]], HDL response to hormone replacement, augmented OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=133430 133430]], Migraine, susceptibility to OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=133430 133430]], Myocardial infarction, susceptibility to OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=133430 133430]] | ||
==About this Structure== | ==About this Structure== | ||
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[[Category: Rajan, S S.]] | [[Category: Rajan, S S.]] | ||
[[Category: Sharma, S K.]] | [[Category: Sharma, S K.]] | ||
- | [[Category: 17M]] | ||
[[Category: estrogen receptor]] | [[Category: estrogen receptor]] | ||
[[Category: grip peptide]] | [[Category: grip peptide]] | ||
[[Category: lbd]] | [[Category: lbd]] | ||
- | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 31 02:00:24 2008'' |
Revision as of 23:00, 30 March 2008
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, resolution 1.78Å | |||||||
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Ligands: | , | ||||||
Gene: | ESR1, ESR, NR3A1 (Homo sapiens) | ||||||
Related: | 2B1V, 2B23
| ||||||
Resources: | FirstGlance, OCA, PDBsum, RCSB | ||||||
Coordinates: | save as pdb, mmCIF, xml |
Human estrogen receptor alpha ligand-binding domain in complex with 17methyl-17alpha-dihydroequilenin and a glucoc interacting protein 1 NR box II peptide
About this Structure
2B1Z is a Protein complex structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.
Page seeded by OCA on Mon Mar 31 02:00:24 2008