5l4x
From Proteopedia
(Difference between revisions)
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of FimH lectin domain in complex with 4-Deoxy-Heptylmannoside== | |
| - | + | <StructureSection load='5l4x' size='340' side='right' caption='[[5l4x]], [[Resolution|resolution]] 1.90Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[5l4x]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Ecoli Ecoli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5L4X OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5L4X FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=6KU:4-Deoxy-Heptylmannoside'>6KU</scene></td></tr> | |
| - | [[Category: | + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">fimH, b4320, JW4283 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=83333 ECOLI])</td></tr> |
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5l4x FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5l4x OCA], [http://pdbe.org/5l4x PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5l4x RCSB], [http://www.ebi.ac.uk/pdbsum/5l4x PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5l4x ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/FIMH_ECOLI FIMH_ECOLI]] Involved in regulation of length and mediation of adhesion of type 1 fimbriae (but not necessary for the production of fimbriae). Adhesin responsible for the binding to D-mannose. It is laterally positioned at intervals in the structure of the type 1 fimbriae. In order to integrate FimH in the fimbriae FimF and FimG are needed. | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Ecoli]] | ||
| + | [[Category: Ernst, B]] | ||
| + | [[Category: Jakob, R P]] | ||
| + | [[Category: Maier, T]] | ||
| + | [[Category: Rabbani, S]] | ||
| + | [[Category: Zihlmann, P]] | ||
| + | [[Category: Carbohydrate]] | ||
| + | [[Category: Cell adhesion]] | ||
| + | [[Category: Fimh]] | ||
| + | [[Category: Lectin]] | ||
| + | [[Category: Mannose]] | ||
| + | [[Category: Sugar binding protein]] | ||
| + | [[Category: Type 1 pilus]] | ||
| + | [[Category: Urinary tract infection]] | ||
| + | [[Category: Uti]] | ||
Revision as of 08:39, 16 November 2017
Crystal structure of FimH lectin domain in complex with 4-Deoxy-Heptylmannoside
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Categories: Ecoli | Ernst, B | Jakob, R P | Maier, T | Rabbani, S | Zihlmann, P | Carbohydrate | Cell adhesion | Fimh | Lectin | Mannose | Sugar binding protein | Type 1 pilus | Urinary tract infection | Uti
