5lo8
From Proteopedia
(Difference between revisions)
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| - | '''Unreleased structure''' | ||
| - | The | + | ==The C2B domain of Rabphilin 3A in complex with PI(4,5)P2== |
| - | + | <StructureSection load='5lo8' size='340' side='right' caption='[[5lo8]], [[Resolution|resolution]] 2.50Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[5lo8]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Buffalo_rat Buffalo rat]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5LO8 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5LO8 FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=PIO:[(2R)-2-OCTANOYLOXY-3-[OXIDANYL-[(1R,2R,3S,4R,5R,6S)-2,3,6-TRIS(OXIDANYL)-4,5-DIPHOSPHONOOXY-CYCLOHEXYL]OXY-PHOSPHORYL]OXY-PROPYL]+OCTANOATE'>PIO</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | |
| - | [[Category: | + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">Rph3a ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10116 Buffalo rat])</td></tr> |
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5lo8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5lo8 OCA], [http://pdbe.org/5lo8 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5lo8 RCSB], [http://www.ebi.ac.uk/pdbsum/5lo8 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5lo8 ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/RP3A_RAT RP3A_RAT]] Protein transport. Probably involved with Ras-related protein Rab-3A in synaptic vesicle traffic and/or synaptic vesicle fusion. Could play a role in neurotransmitter release by regulating membrane flow in the nerve terminal. | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Buffalo rat]] | ||
| + | [[Category: Ferrer-Orta, C]] | ||
| + | [[Category: Verdaguer, N]] | ||
| + | [[Category: C2 domain]] | ||
| + | [[Category: Pip2]] | ||
| + | [[Category: Protein transport]] | ||
| + | [[Category: Vesicle fusion]] | ||
Revision as of 08:42, 16 November 2017
The C2B domain of Rabphilin 3A in complex with PI(4,5)P2
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