5h6v
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Structure of Zika virus protease in complex with a dipeptide inhibitor== | |
| - | + | <StructureSection load='5h6v' size='340' side='right' caption='[[5h6v]], [[Resolution|resolution]] 2.42Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[5h6v]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Zikv Zikv]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5H6V OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5H6V FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=7HS:(S)-2-acetamido-6-amino-N-((S)-5-guanidino-1-oxopentan-2-yl)hexanamide'>7HS</scene></td></tr> | |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5h6v FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5h6v OCA], [http://pdbe.org/5h6v PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5h6v RCSB], [http://www.ebi.ac.uk/pdbsum/5h6v PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5h6v ProSAT]</span></td></tr> |
| + | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/H8XX12_ZIKV H8XX12_ZIKV]] Peptide 2k: Functions as a signal peptide for NS4B and is required for the interferon antagonism activity of the latter.[SAAS:SAAS00882589] | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Zikv]] | ||
| + | [[Category: Chen, M]] | ||
| + | [[Category: Zhang, Z]] | ||
| + | [[Category: Non-structural protein 3]] | ||
| + | [[Category: Serine protease]] | ||
| + | [[Category: Viral protein-inhibitor complex]] | ||
Revision as of 09:44, 16 November 2017
Structure of Zika virus protease in complex with a dipeptide inhibitor
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