5nzx
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of DNA cross-link repair protein 1A in complex with Ceftriaxone (alternative site)== | |
| - | + | <StructureSection load='5nzx' size='340' side='right' caption='[[5nzx]], [[Resolution|resolution]] 1.47Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[5nzx]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5NZX OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5NZX FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=9F2:Ceftriaxone'>9F2</scene>, <scene name='pdbligand=NI:NICKEL+(II)+ION'>NI</scene></td></tr> | |
| - | [[Category: | + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">DCLRE1A, KIAA0086, SNM1, SNM1A ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr> |
| - | [[Category: Aitkenhead, H, | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5nzx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5nzx OCA], [http://pdbe.org/5nzx PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5nzx RCSB], [http://www.ebi.ac.uk/pdbsum/5nzx PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5nzx ProSAT]</span></td></tr> |
| - | [[Category: | + | </table> |
| - | [[Category: Newman, J | + | == Function == |
| - | [[Category: | + | [[http://www.uniprot.org/uniprot/DCR1A_HUMAN DCR1A_HUMAN]] May be required for DNA interstrand cross-link repair. Also required for checkpoint mediated cell cycle arrest in early prophase in response to mitotic spindle poisons.<ref>PMID:15542852</ref> |
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Human]] | ||
| + | [[Category: Aitkenhead, H]] | ||
| + | [[Category: Arrowsmith, C H]] | ||
| + | [[Category: Bountra, C]] | ||
| + | [[Category: Burgess-Brown, N A]] | ||
| + | [[Category: Delft, F von]] | ||
| + | [[Category: Edwards, A]] | ||
| + | [[Category: Gileadi, O]] | ||
| + | [[Category: Krojer, T]] | ||
| + | [[Category: Kupinska, K]] | ||
| + | [[Category: Newman, J A]] | ||
| + | [[Category: Talon, R]] | ||
| + | [[Category: Cephalosporin]] | ||
| + | [[Category: Cross-link repair]] | ||
| + | [[Category: Dclre1a]] | ||
| + | [[Category: Exonulcease]] | ||
| + | [[Category: Hydrolase]] | ||
Revision as of 09:57, 16 November 2017
Crystal structure of DNA cross-link repair protein 1A in complex with Ceftriaxone (alternative site)
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Categories: Human | Aitkenhead, H | Arrowsmith, C H | Bountra, C | Burgess-Brown, N A | Delft, F von | Edwards, A | Gileadi, O | Krojer, T | Kupinska, K | Newman, J A | Talon, R | Cephalosporin | Cross-link repair | Dclre1a | Exonulcease | Hydrolase
