Vpu protein
From Proteopedia
(Difference between revisions)
| Line 1: | Line 1: | ||
| - | <StructureSection load='4p6z' size='340' side='right' caption='HIV-1 Vpu protein (dark olive) complex with adapter-related protein complex 1 subunits γ-1 (gold), σ-1a (khaki), μ-1 (olive green), β-1 (green) (PDB code [[4p6z]])' scene=''> | + | <StructureSection load='4p6z' size='340' side='right' caption='HIV-1 Vpu protein (dark olive) complex with adapter-related protein complex 1 subunits γ-1 (gold), σ-1a (khaki), μ-1 (olive green), β-1 (green) (PDB code [[4p6z]])' scene='75/750240/Cv/2'> |
== Function == | == Function == | ||
| - | '''Vpu protein''' (Vpu) or '''viral protein U''' is a viroporin encoded by HIV-1<ref>PMID:26247957</ref>. Vpu is a multifunctional enhancer of viral particle release<ref>PMID:12941395</ref>. | + | '''Vpu protein''' (Vpu) or '''viral protein U''' is a viroporin encoded by HIV-1<ref>PMID:26247957</ref>. Vpu is a multifunctional enhancer of viral particle release<ref>PMID:12941395</ref>. <scene name='75/750240/Cv/1'>HIV-1 Vpu protein complex with adapter-related protein complex 1 subunits γ-1, σ-1a, μ-1, β-1</scene> (PDB code [[4p6z]]). |
For details see [[HIV and accessory proteins]]. | For details see [[HIV and accessory proteins]]. | ||
Revision as of 13:26, 16 November 2017
| |||||||||||
3D Structures of Vpu protein
Updated on 16-November-2017
2n28 – Vpu - HIV-1 - NMR
4p6z – Vpu + adapter-related protein complex 1 subunits γ-1, σ-1a, μ-1, β-1 – HIV-1
1pi7, 1pi8, 1pje, 2gof, 2goh – Vpu trans-membrane domain - NMR
1vpu, 2n29, 2k7y – Vpu cytoplasmic domain - NMR
4p6z – Vpu cytoplasmic domain + BST2 + AP-1 core
References
- ↑ Gonzalez ME. Vpu Protein: The Viroporin Encoded by HIV-1. Viruses. 2015 Aug 4;7(8):4352-68. doi: 10.3390/v7082824. PMID:26247957 doi:http://dx.doi.org/10.3390/v7082824
- ↑ Bour S, Strebel K. The HIV-1 Vpu protein: a multifunctional enhancer of viral particle release. Microbes Infect. 2003 Sep;5(11):1029-39. PMID:12941395
