4pdc
From Proteopedia
(Difference between revisions)
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<StructureSection load='4pdc' size='340' side='right' caption='[[4pdc]], [[Resolution|resolution]] 1.99Å' scene=''> | <StructureSection load='4pdc' size='340' side='right' caption='[[4pdc]], [[Resolution|resolution]] 1.99Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[4pdc]] is a 6 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4PDC OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4PDC FirstGlance]. <br> | + | <table><tr><td colspan='2'>[[4pdc]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Cowpx Cowpx] and [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4PDC OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4PDC FirstGlance]. <br> |
</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4ffe|4ffe]], [[1mpu|1mpu]], [[1hyr|1hyr]], [[1jsk|1jsk]], [[1kcg|1kcg]]</td></tr> | </td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4ffe|4ffe]], [[1mpu|1mpu]], [[1hyr|1hyr]], [[1jsk|1jsk]], [[1kcg|1kcg]]</td></tr> | ||
| + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">KLRK1, D12S2489E, NKG2D ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN]), CPXV018 CDS ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10243 COWPX])</td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4pdc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4pdc OCA], [http://pdbe.org/4pdc PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4pdc RCSB], [http://www.ebi.ac.uk/pdbsum/4pdc PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4pdc ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4pdc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4pdc OCA], [http://pdbe.org/4pdc PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4pdc RCSB], [http://www.ebi.ac.uk/pdbsum/4pdc PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4pdc ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
[[http://www.uniprot.org/uniprot/NKG2D_HUMAN NKG2D_HUMAN]] Receptor for MICA, MICB, ULBP1, ULBP2, ULBP3 (ULBP2>ULBP1>ULBP3) and ULBP4. Plays a role as a receptor for the recognition of MHC class I HLA-E molecules by NK cells and some cytotoxic T-cells. Involved in the immune surveillance exerted by T- and B-lymphocytes. | [[http://www.uniprot.org/uniprot/NKG2D_HUMAN NKG2D_HUMAN]] Receptor for MICA, MICB, ULBP1, ULBP2, ULBP3 (ULBP2>ULBP1>ULBP3) and ULBP4. Plays a role as a receptor for the recognition of MHC class I HLA-E molecules by NK cells and some cytotoxic T-cells. Involved in the immune surveillance exerted by T- and B-lymphocytes. | ||
| - | |||
| - | ==See Also== | ||
| - | *[[NK cell receptor|NK cell receptor]] | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| + | [[Category: Cowpx]] | ||
| + | [[Category: Human]] | ||
[[Category: Structural genomic]] | [[Category: Structural genomic]] | ||
[[Category: Fremont, D H]] | [[Category: Fremont, D H]] | ||
Revision as of 08:38, 22 November 2017
Crystal structure of Cowpox virus CPXV018 (OMCP) bound to human NKG2D
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