4py1

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<StructureSection load='4py1' size='340' side='right' caption='[[4py1]], [[Resolution|resolution]] 2.16&Aring;' scene=''>
<StructureSection load='4py1' size='340' side='right' caption='[[4py1]], [[Resolution|resolution]] 2.16&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[4py1]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4PY1 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4PY1 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[4py1]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4PY1 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4PY1 FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=2YK:6-[(2,5-DIMETHOXYPHENYL)SULFANYL]-3-(1-METHYL-1H-PYRAZOL-4-YL)[1,2,4]TRIAZOLO[4,3-B]PYRIDAZINE'>2YK</scene></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=2YK:6-[(2,5-DIMETHOXYPHENYL)SULFANYL]-3-(1-METHYL-1H-PYRAZOL-4-YL)[1,2,4]TRIAZOLO[4,3-B]PYRIDAZINE'>2YK</scene></td></tr>
<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=PTR:O-PHOSPHOTYROSINE'>PTR</scene></td></tr>
<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=PTR:O-PHOSPHOTYROSINE'>PTR</scene></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">TYK2 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Non-specific_protein-tyrosine_kinase Non-specific protein-tyrosine kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.10.2 2.7.10.2] </span></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Non-specific_protein-tyrosine_kinase Non-specific protein-tyrosine kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.10.2 2.7.10.2] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4py1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4py1 OCA], [http://pdbe.org/4py1 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4py1 RCSB], [http://www.ebi.ac.uk/pdbsum/4py1 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4py1 ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4py1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4py1 OCA], [http://pdbe.org/4py1 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4py1 RCSB], [http://www.ebi.ac.uk/pdbsum/4py1 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4py1 ProSAT]</span></td></tr>
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==See Also==
==See Also==
*[[Student Project 5 for UMass Chemistry 423 Spring 2015|Student Project 5 for UMass Chemistry 423 Spring 2015]]
*[[Student Project 5 for UMass Chemistry 423 Spring 2015|Student Project 5 for UMass Chemistry 423 Spring 2015]]
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*[[Tyrosine kinase|Tyrosine kinase]]
 
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Human]]
[[Category: Non-specific protein-tyrosine kinase]]
[[Category: Non-specific protein-tyrosine kinase]]
[[Category: Han, S]]
[[Category: Han, S]]

Revision as of 08:46, 22 November 2017

Crystal structure of Tyk2 in complex with compound 15, 6-((2,5-dimethoxyphenyl)thio)-3-(1-methyl-1H-pyrazol-4-yl)-[1,2,4]triazolo[4,3-b]pyridazine

4py1, resolution 2.16Å

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