4rx9

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<StructureSection load='4rx9' size='340' side='right' caption='[[4rx9]], [[Resolution|resolution]] 1.75&Aring;' scene=''>
<StructureSection load='4rx9' size='340' side='right' caption='[[4rx9]], [[Resolution|resolution]] 1.75&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[4rx9]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4RX9 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4RX9 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[4rx9]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4RX9 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4RX9 FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=3YT:2-{[(1R,2S)-2-AMINOCYCLOHEXYL]AMINO}-4-{[3-(2H-1,2,3-TRIAZOL-2-YL)PHENYL]AMINO}PYRIMIDINE-5-CARBOXAMIDE'>3YT</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=3YT:2-{[(1R,2S)-2-AMINOCYCLOHEXYL]AMINO}-4-{[3-(2H-1,2,3-TRIAZOL-2-YL)PHENYL]AMINO}PYRIMIDINE-5-CARBOXAMIDE'>3YT</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4rx7|4rx7]], [[4rx8|4rx8]]</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4rx7|4rx7]], [[4rx8|4rx8]]</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">SYK ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Non-specific_protein-tyrosine_kinase Non-specific protein-tyrosine kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.10.2 2.7.10.2] </span></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Non-specific_protein-tyrosine_kinase Non-specific protein-tyrosine kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.10.2 2.7.10.2] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4rx9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4rx9 OCA], [http://pdbe.org/4rx9 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4rx9 RCSB], [http://www.ebi.ac.uk/pdbsum/4rx9 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4rx9 ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4rx9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4rx9 OCA], [http://pdbe.org/4rx9 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4rx9 RCSB], [http://www.ebi.ac.uk/pdbsum/4rx9 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4rx9 ProSAT]</span></td></tr>
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</div>
</div>
<div class="pdbe-citations 4rx9" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 4rx9" style="background-color:#fffaf0;"></div>
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==See Also==
 
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*[[Tyrosine kinase|Tyrosine kinase]]
 
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Human]]
[[Category: Non-specific protein-tyrosine kinase]]
[[Category: Non-specific protein-tyrosine kinase]]
[[Category: Lee, C C]]
[[Category: Lee, C C]]
[[Category: Transferase-transferase inhibitor complex]]
[[Category: Transferase-transferase inhibitor complex]]

Revision as of 09:12, 22 November 2017

SYK Catalytic Domain Complexed with a Potent Pyrimidine Inhibitor

4rx9, resolution 1.75Å

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