4w5c
From Proteopedia
(Difference between revisions)
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<StructureSection load='4w5c' size='340' side='right' caption='[[4w5c]], [[Resolution|resolution]] 3.27Å' scene=''> | <StructureSection load='4w5c' size='340' side='right' caption='[[4w5c]], [[Resolution|resolution]] 3.27Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[4w5c]] is a 5 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4W5C OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4W5C FirstGlance]. <br> | + | <table><tr><td colspan='2'>[[4w5c]] is a 5 chain structure with sequence from [http://en.wikipedia.org/wiki/Trycr Trycr]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4W5C OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4W5C FirstGlance]. <br> |
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=3H5:N-(1H-BENZIMIDAZOL-2-YL)-1,3-DIMETHYL-1H-PYRAZOLE-4-CARBOXAMIDE'>3H5</scene>, <scene name='pdbligand=3H6:N-(1H-BENZIMIDAZOL-2-YL)-3-(4-FLUOROPHENYL)-1H-PYRAZOLE-4-CARBOXAMIDE'>3H6</scene>, <scene name='pdbligand=3H7:4,6-DIFLUORO-1,3-BENZOTHIAZOL-2-AMINE'>3H7</scene></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=3H5:N-(1H-BENZIMIDAZOL-2-YL)-1,3-DIMETHYL-1H-PYRAZOLE-4-CARBOXAMIDE'>3H5</scene>, <scene name='pdbligand=3H6:N-(1H-BENZIMIDAZOL-2-YL)-3-(4-FLUOROPHENYL)-1H-PYRAZOLE-4-CARBOXAMIDE'>3H6</scene>, <scene name='pdbligand=3H7:4,6-DIFLUORO-1,3-BENZOTHIAZOL-2-AMINE'>3H7</scene></td></tr> | ||
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3kku|3kku]], [[4pi3|4pi3]], [[4pi4|4pi4]], [[4w5b|4w5b]]</td></tr> | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3kku|3kku]], [[4pi3|4pi3]], [[4pi4|4pi4]], [[4w5b|4w5b]]</td></tr> | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Cruzipain]] | [[Category: Cruzipain]] | ||
| + | [[Category: Trycr]] | ||
[[Category: Craik, C S]] | [[Category: Craik, C S]] | ||
[[Category: McKerrow, J H]] | [[Category: McKerrow, J H]] | ||
Revision as of 09:22, 22 November 2017
Crystal structure analysis of cruzain with three Fragments: 1 (N-(1H-benzimidazol-2-yl)-1,3-dimethyl-pyrazole-4-carboxamide), 6 (2-amino-4,6-difluorobenzothiazole) and 9 (N-(1H-benzimidazol-2-yl)-3-(4-fluorophenyl)-1H-pyrazole-4-carboxamide).
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