4wnp

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<StructureSection load='4wnp' size='340' side='right' caption='[[4wnp]], [[Resolution|resolution]] 1.88&Aring;' scene=''>
<StructureSection load='4wnp' size='340' side='right' caption='[[4wnp]], [[Resolution|resolution]] 1.88&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[4wnp]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4WNP OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4WNP FirstGlance]. <br>
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<table><tr><td colspan='2'>[[4wnp]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4WNP OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4WNP FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=3RJ:N~2~-(1H-BENZIMIDAZOL-6-YL)-N~4~-(5-CYCLOBUTYL-1H-PYRAZOL-3-YL)QUINAZOLINE-2,4-DIAMINE'>3RJ</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=3RJ:N~2~-(1H-BENZIMIDAZOL-6-YL)-N~4~-(5-CYCLOBUTYL-1H-PYRAZOL-3-YL)QUINAZOLINE-2,4-DIAMINE'>3RJ</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=TPO:PHOSPHOTHREONINE'>TPO</scene></td></tr>
<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=TPO:PHOSPHOTHREONINE'>TPO</scene></td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4wno|4wno]]</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4wno|4wno]]</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">ULK1, KIAA0722 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Non-specific_serine/threonine_protein_kinase Non-specific serine/threonine protein kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.11.1 2.7.11.1] </span></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Non-specific_serine/threonine_protein_kinase Non-specific serine/threonine protein kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.11.1 2.7.11.1] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4wnp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4wnp OCA], [http://pdbe.org/4wnp PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4wnp RCSB], [http://www.ebi.ac.uk/pdbsum/4wnp PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4wnp ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4wnp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4wnp OCA], [http://pdbe.org/4wnp PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4wnp RCSB], [http://www.ebi.ac.uk/pdbsum/4wnp PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4wnp ProSAT]</span></td></tr>
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</div>
</div>
<div class="pdbe-citations 4wnp" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 4wnp" style="background-color:#fffaf0;"></div>
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==See Also==
 
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*[[Serine/threonine protein kinase|Serine/threonine protein kinase]]
 
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Human]]
[[Category: Non-specific serine/threonine protein kinase]]
[[Category: Non-specific serine/threonine protein kinase]]
[[Category: Lazarus, M B]]
[[Category: Lazarus, M B]]
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[[Category: Inhibitor]]
[[Category: Inhibitor]]
[[Category: Kinase]]
[[Category: Kinase]]
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[[Category: Transferase-transferase inhibitor complex]]

Revision as of 09:27, 22 November 2017

Structure of ULK1 bound to a potent inhibitor

4wnp, resolution 1.88Å

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