4y2h

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<StructureSection load='4y2h' size='340' side='right' caption='[[4y2h]], [[Resolution|resolution]] 2.37&Aring;' scene=''>
<StructureSection load='4y2h' size='340' side='right' caption='[[4y2h]], [[Resolution|resolution]] 2.37&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[4y2h]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4Y2H OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4Y2H FirstGlance]. <br>
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<table><tr><td colspan='2'>[[4y2h]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4Y2H OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4Y2H FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=49K:N-{[5-(4-FLUOROPHENYL)-1H-PYRAZOL-4-YL]METHYL}-N-METHYLETHANE-1,2-DIAMINE'>49K</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=SAH:S-ADENOSYL-L-HOMOCYSTEINE'>SAH</scene></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=49K:N-{[5-(4-FLUOROPHENYL)-1H-PYRAZOL-4-YL]METHYL}-N-METHYLETHANE-1,2-DIAMINE'>49K</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=SAH:S-ADENOSYL-L-HOMOCYSTEINE'>SAH</scene></td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4y30|4y30]]</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4y30|4y30]]</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">PRMT6, HRMT1L6 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4y2h FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4y2h OCA], [http://pdbe.org/4y2h PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4y2h RCSB], [http://www.ebi.ac.uk/pdbsum/4y2h PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4y2h ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4y2h FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4y2h OCA], [http://pdbe.org/4y2h PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4y2h RCSB], [http://www.ebi.ac.uk/pdbsum/4y2h PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4y2h ProSAT]</span></td></tr>
</table>
</table>
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Human]]
[[Category: Boriack-Sjodin, P A]]
[[Category: Boriack-Sjodin, P A]]
[[Category: Swinger, K K]]
[[Category: Swinger, K K]]
[[Category: Transferase]]
[[Category: Transferase]]

Revision as of 09:38, 22 November 2017

Crystal structure of human protein arginine methyltransferase PRMT6 bound to SAH and an aryl pyrazole inhibitor

4y2h, resolution 2.37Å

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