This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


5hi4

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Line 3: Line 3:
<StructureSection load='5hi4' size='340' side='right' caption='[[5hi4]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
<StructureSection load='5hi4' size='340' side='right' caption='[[5hi4]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
-
<table><tr><td colspan='2'>[[5hi4]] is a 7 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5HI4 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5HI4 FirstGlance]. <br>
+
<table><tr><td colspan='2'>[[5hi4]] is a 7 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5HI4 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5HI4 FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=63P:(9S,17R)-6-chloro-N-methyl-9-{[(1-methyl-1H-pyrazol-5-yl)carbonyl]amino}-10,19-dioxo-2-oxa-11,18-diazaspiro[cyclopentane-1,21-tetracyclo[20.2.2.2~12,15~.1~3,7~]nonacosane]-1(24),3(29),4,6,12,14,22,25,27-nonaene-17-carboxamide'>63P</scene></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=63P:(9S,17R)-6-chloro-N-methyl-9-{[(1-methyl-1H-pyrazol-5-yl)carbonyl]amino}-10,19-dioxo-2-oxa-11,18-diazaspiro[cyclopentane-1,21-tetracyclo[20.2.2.2~12,15~.1~3,7~]nonacosane]-1(24),3(29),4,6,12,14,22,25,27-nonaene-17-carboxamide'>63P</scene></td></tr>
<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACE:ACETYL+GROUP'>ACE</scene></td></tr>
<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACE:ACETYL+GROUP'>ACE</scene></td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5hhv|5hhv]], [[5hhx|5hhx]], [[5hi3|5hi3]], [[5hi5|5hi5]]</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5hhv|5hhv]], [[5hhx|5hhx]], [[5hi3|5hi3]], [[5hi5|5hi5]]</td></tr>
 +
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">IL17A, CTLA8, IL17 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5hi4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5hi4 OCA], [http://pdbe.org/5hi4 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5hi4 RCSB], [http://www.ebi.ac.uk/pdbsum/5hi4 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5hi4 ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5hi4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5hi4 OCA], [http://pdbe.org/5hi4 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5hi4 RCSB], [http://www.ebi.ac.uk/pdbsum/5hi4 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5hi4 ProSAT]</span></td></tr>
</table>
</table>
Line 24: Line 25:
__TOC__
__TOC__
</StructureSection>
</StructureSection>
 +
[[Category: Human]]
[[Category: Liu, S]]
[[Category: Liu, S]]
[[Category: Il-17a]]
[[Category: Il-17a]]

Revision as of 09:59, 22 November 2017

Binding site elucidation and structure guided design of macrocyclic IL-17A antagonists

5hi4, resolution 1.80Å

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/5hi4"
Personal tools