5hmh

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<StructureSection load='5hmh' size='340' side='right' caption='[[5hmh]], [[Resolution|resolution]] 1.79&Aring;' scene=''>
<StructureSection load='5hmh' size='340' side='right' caption='[[5hmh]], [[Resolution|resolution]] 1.79&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[5hmh]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5HMH OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5HMH FirstGlance]. <br>
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<table><tr><td colspan='2'>[[5hmh]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5HMH OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5HMH FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=62R:4-[2-(4-{[(2R,3S)-2-PROPYL-1-{[4-(TRIFLUOROMETHYL)PYRIDIN-3-YL]CARBONYL}-3-{[5-(TRIFLUOROMETHYL)THIOPHEN-3-YL]OXY}PIPERIDIN-3-YL]CARBONYL}PIPERAZIN-1-YL)PHENOXY]BUTANOIC+ACID'>62R</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=62R:4-[2-(4-{[(2R,3S)-2-PROPYL-1-{[4-(TRIFLUOROMETHYL)PYRIDIN-3-YL]CARBONYL}-3-{[5-(TRIFLUOROMETHYL)THIOPHEN-3-YL]OXY}PIPERIDIN-3-YL]CARBONYL}PIPERAZIN-1-YL)PHENOXY]BUTANOIC+ACID'>62R</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5hmk|5hmk]], [[5hmi|5hmi]]</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5hmk|5hmk]], [[5hmi|5hmi]]</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5hmh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5hmh OCA], [http://pdbe.org/5hmh PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5hmh RCSB], [http://www.ebi.ac.uk/pdbsum/5hmh PDBsum]</span></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">MDM2 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5hmh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5hmh OCA], [http://pdbe.org/5hmh PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5hmh RCSB], [http://www.ebi.ac.uk/pdbsum/5hmh PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5hmh ProSAT]</span></td></tr>
</table>
</table>
== Disease ==
== Disease ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Human]]
[[Category: Scapin, G]]
[[Category: Scapin, G]]
[[Category: E3 ubiquitin-protein ligase]]
[[Category: E3 ubiquitin-protein ligase]]

Revision as of 09:59, 22 November 2017

HDM2 in complex with a 3,3-Disubstituted Piperidine

5hmh, resolution 1.79Å

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