5m79

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'''Unreleased structure'''
 
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The entry 5m79 is ON HOLD until Paper Publication
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==Blood group synthase AAGlyB in complex with UMP and cryoprotected with glycerol==
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<StructureSection load='5m79' size='340' side='right' caption='[[5m79]], [[Resolution|resolution]] 1.30&Aring;' scene=''>
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Authors:
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== Structural highlights ==
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<table><tr><td colspan='2'>[[5m79]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5M79 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5M79 FirstGlance]. <br>
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Description:
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=U5P:URIDINE-5-MONOPHOSPHATE'>U5P</scene></td></tr>
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[[Category: Unreleased Structures]]
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3zgf|3zgf]], [[3zgg|3zgg]]</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5m79 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5m79 OCA], [http://pdbe.org/5m79 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5m79 RCSB], [http://www.ebi.ac.uk/pdbsum/5m79 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5m79 ProSAT]</span></td></tr>
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</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/BGAT_HUMAN BGAT_HUMAN]] This protein is the basis of the ABO blood group system. The histo-blood group ABO involves three carbohydrate antigens: A, B, and H. A, B, and AB individuals express a glycosyltransferase activity that converts the H antigen to the A antigen (by addition of UDP-GalNAc) or to the B antigen (by addition of UDP-Gal), whereas O individuals lack such activity.
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__TOC__
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</StructureSection>
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[[Category: Rocha, J]]
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[[Category: Royant, A]]
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[[Category: Blood group synthase]]
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[[Category: Cis-ab mutant]]
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[[Category: Dual-specificity]]
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[[Category: Glycosyltransferase]]
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[[Category: Transferase]]

Revision as of 06:06, 29 November 2017

Blood group synthase AAGlyB in complex with UMP and cryoprotected with glycerol

5m79, resolution 1.30Å

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