1gdi

From Proteopedia

(Difference between revisions)

Revision as of 06:35, 29 November 2017

CRYSTAL STRUCTURE OF FERRIC COMPLEXES OF THE YELLOW LUPIN LEGHEMOGLOBIN WITH ISOQUINOLINE AT 1.8 ANGSTROMS RESOLUTION (RUSSIAN)

Structural highlights

1gdi is a 1 chain structure with sequence from European yellow lupine. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Ligands:	,
Resources:	FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

[LGB2_LUPLU] Provides oxygen to the bacteroids. This role is essential for symbiotic nitrogen fixation.

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

Publication Abstract from PubMed

Haemoglobins have the ability to discriminate between oxygen and other diatomic molecules. To further understanding of this process the X-ray crystal structures of carbonmonoxy and nitrosyl-leghaemoglobin have been determined at 1.8 A resolution. The ligand geometry is discussed in detail and the controversial issue of bent versus linear carbon monoxide binding is addressed. The bond angle of 160 degrees for CO-leghaemoglobin is in conflict with recent spectroscopy results on myoglobin but is consistent with angles obtained for myoglobin X-ray crystal structures. In contrast to the numerous carbon monoxide studies, very little stereochemical information is available for the nitric oxide adduct of haemoglobin. This is provided by the X-ray structure of NO-leghaemoglobin, which conforms to expected geometry with an Fe-NO angle of 147 degrees and a lengthened iron-proximal histidine bond. Thus crystallographic evidence is given for the predicted weakening of this bond on the binding of nitric oxide.

The binding of carbon monoxide and nitric oxide to leghaemoglobin in comparison with other haemoglobins.,Harutyunyan EH, Safonova TN, Kuranova IP, Popov AN, Teplyakov AV, Obmolova GV, Valnshtein BK, Dodson GG, Wilson JC J Mol Biol. 1996 Nov 22;264(1):152-61. PMID:8950274^[1]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.

References

↑ Harutyunyan EH, Safonova TN, Kuranova IP, Popov AN, Teplyakov AV, Obmolova GV, Valnshtein BK, Dodson GG, Wilson JC. The binding of carbon monoxide and nitric oxide to leghaemoglobin in comparison with other haemoglobins. J Mol Biol. 1996 Nov 22;264(1):152-61. PMID:8950274

1 Structural highlights
2 Function
3 Evolutionary Conservation
4 Publication Abstract from PubMed
5 See Also
6 References

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/1gdi"

Categories: European yellow lupine | Harutyunyan, E | Kuranova, I | Safonova, T | Oxygen transport

@@ Line 1: / Line 1: @@
 ==CRYSTAL STRUCTURE OF FERRIC COMPLEXES OF THE YELLOW LUPIN LEGHEMOGLOBIN WITH ISOQUINOLINE AT 1.8 ANGSTROMS RESOLUTION (RUSSIAN)==
 <StructureSection load='1gdi' size='340' side='right' caption='[[1gdi]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
 == Structural highlights ==
-<table><tr><td colspan='2'>[[1gdi]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/European_yellow_lupin European yellow lupin]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1GDI OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1GDI FirstGlance]. <br>
+<table><tr><td colspan='2'>[[1gdi]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/European_yellow_lupine European yellow lupine]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1GDI OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1GDI FirstGlance]. <br>
 </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CMO:CARBON+MONOXIDE'>CMO</scene>, <scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene></td></tr>
-<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1gdi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1gdi OCA], [http://pdbe.org/1gdi PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1gdi RCSB], [http://www.ebi.ac.uk/pdbsum/1gdi PDBsum]</span></td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1gdi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1gdi OCA], [http://pdbe.org/1gdi PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1gdi RCSB], [http://www.ebi.ac.uk/pdbsum/1gdi PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1gdi ProSAT]</span></td></tr>
 </table>
 == Function ==
@@ Line 34: / Line 35: @@
 __TOC__
 </StructureSection>
-[[Category: European yellow lupin]]
+[[Category: European yellow lupine]]
 [[Category: Harutyunyan, E]]
 [[Category: Kuranova, I]]
 [[Category: Safonova, T]]
 [[Category: Oxygen transport]]

1gdi

From Proteopedia

Revision as of 06:35, 29 November 2017

CRYSTAL STRUCTURE OF FERRIC COMPLEXES OF THE YELLOW LUPIN LEGHEMOGLOBIN WITH ISOQUINOLINE AT 1.8 ANGSTROMS RESOLUTION (RUSSIAN)

Structural highlights

Function

Evolutionary Conservation

Publication Abstract from PubMed

See Also

References

Contents

Proteopedia Page Contributors and Editors (what is this?)

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