2cag
From Proteopedia
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|PDB= 2cag |SIZE=350|CAPTION= <scene name='initialview01'>2cag</scene>, resolution 2.7Å | |PDB= 2cag |SIZE=350|CAPTION= <scene name='initialview01'>2cag</scene>, resolution 2.7Å | ||
|SITE= <scene name='pdbsite=DH:Distal+HIS'>DH</scene> and <scene name='pdbsite=PT:Proximal+TYR'>PT</scene> | |SITE= <scene name='pdbsite=DH:Distal+HIS'>DH</scene> and <scene name='pdbsite=PT:Proximal+TYR'>PT</scene> | ||
| - | |LIGAND= <scene name='pdbligand=HEM:PROTOPORPHYRIN IX CONTAINING FE'>HEM</scene> | + | |LIGAND= <scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene>, <scene name='pdbligand=OMT:S-DIOXYMETHIONINE'>OMT</scene> |
| - | |ACTIVITY= [http://en.wikipedia.org/wiki/Catalase Catalase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.11.1.6 1.11.1.6] | + | |ACTIVITY= <span class='plainlinks'>[http://en.wikipedia.org/wiki/Catalase Catalase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.11.1.6 1.11.1.6] </span> |
|GENE= | |GENE= | ||
| + | |DOMAIN= | ||
| + | |RELATEDENTRY= | ||
| + | |RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2cag FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2cag OCA], [http://www.ebi.ac.uk/pdbsum/2cag PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=2cag RCSB]</span> | ||
}} | }} | ||
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[[Category: Hajdu, J.]] | [[Category: Hajdu, J.]] | ||
[[Category: Jouve, H M.]] | [[Category: Jouve, H M.]] | ||
| - | [[Category: HEM]] | ||
[[Category: heme]] | [[Category: heme]] | ||
[[Category: hydrogen peroxide]] | [[Category: hydrogen peroxide]] | ||
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[[Category: peroxidase]] | [[Category: peroxidase]] | ||
| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 31 02:18:45 2008'' |
Revision as of 23:18, 30 March 2008
| |||||||
| , resolution 2.7Å | |||||||
|---|---|---|---|---|---|---|---|
| Sites: | and | ||||||
| Ligands: | , | ||||||
| Activity: | Catalase, with EC number 1.11.1.6 | ||||||
| Resources: | FirstGlance, OCA, PDBsum, RCSB | ||||||
| Coordinates: | save as pdb, mmCIF, xml | ||||||
CATALASE COMPOUND II
Overview
Various enzymes use semi-stable ferryl intermediates and free radicals during their catalytic cycle, amongst them haem catalases. Structures for two transient intermediates (compounds I and II) of the NADPH-dependent catalase from Proteus mirabilis (PMC) have been determined by time-resolved X-ray crystallography and single crystal microspectrophotometry. The results show the formation and transformation of the ferryl group in the haem, and the unexpected binding of an anion during this reaction at a site distant from the haem.
About this Structure
2CAG is a Single protein structure of sequence from Proteus mirabilis. The following page contains interesting information on the relation of 2CAG with [Catalase]. Full crystallographic information is available from OCA.
Reference
Ferryl intermediates of catalase captured by time-resolved Weissenberg crystallography and UV-VIS spectroscopy., Gouet P, Jouve HM, Williams PA, Andersson I, Andreoletti P, Nussaume L, Hajdu J, Nat Struct Biol. 1996 Nov;3(11):951-6. PMID:8901874
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