5wt1
From Proteopedia
(Difference between revisions)
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| - | '''Unreleased structure''' | ||
| - | + | ==Pyrococcus abyssi methyltransferase PaTrm5a bound by SAH and cognate tRNA== | |
| - | + | <StructureSection load='5wt1' size='340' side='right' caption='[[5wt1]], [[Resolution|resolution]] 2.60Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[5wt1]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5WT1 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5WT1 FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SAH:S-ADENOSYL-L-HOMOCYSTEINE'>SAH</scene></td></tr> | |
| - | [[ | + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5wt3|5wt3]]</td></tr> |
| - | [[ | + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/tRNA_(guanine(37)-N(1))-methyltransferase tRNA (guanine(37)-N(1))-methyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.1.1.228 2.1.1.228] </span></td></tr> |
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5wt1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5wt1 OCA], [http://pdbe.org/5wt1 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5wt1 RCSB], [http://www.ebi.ac.uk/pdbsum/5wt1 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5wt1 ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/TRM5A_PYRAB TRM5A_PYRAB]] Specifically methylates the N1 position of guanosine-37 in tRNA(Phe). In vitro, can also methylate the C7 position of 4-demethylwyosine (imG-14).<ref>PMID:20382657</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
[[Category: Jia, Q]] | [[Category: Jia, Q]] | ||
[[Category: Wang, C]] | [[Category: Wang, C]] | ||
| + | [[Category: Xie, W]] | ||
| + | [[Category: Methyltransferase]] | ||
| + | [[Category: Transferase-rna complex]] | ||
| + | [[Category: Trm5a]] | ||
| + | [[Category: Wyosine hypermodification]] | ||
Revision as of 06:59, 13 December 2017
Pyrococcus abyssi methyltransferase PaTrm5a bound by SAH and cognate tRNA
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