6bgf
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of cysteine-bound ferrous form of the crosslinked human cysteine dioxygenase== | |
| - | + | <StructureSection load='6bgf' size='340' side='right' caption='[[6bgf]], [[Resolution|resolution]] 2.25Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[6bgf]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6BGF OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6BGF FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CYS:CYSTEINE'>CYS</scene>, <scene name='pdbligand=FE2:FE+(II)+ION'>FE2</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | |
| - | [[Category: | + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Cysteine_dioxygenase Cysteine dioxygenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.13.11.20 1.13.11.20] </span></td></tr> |
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6bgf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6bgf OCA], [http://pdbe.org/6bgf PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6bgf RCSB], [http://www.ebi.ac.uk/pdbsum/6bgf PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6bgf ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/CDO1_HUMAN CDO1_HUMAN]] Initiates several important metabolic pathways related to pyruvate and several sulfurate compounds including sulfate, hypotaurine and taurine. Critical regulator of cellular cysteine concentrations. Has an important role in maintaining the hepatic concentation of intracellular free cysteine within a proper narrow range. | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Cysteine dioxygenase]] | ||
[[Category: Li, J]] | [[Category: Li, J]] | ||
| + | [[Category: Liu, A]] | ||
[[Category: Shin, I]] | [[Category: Shin, I]] | ||
| - | [[Category: | + | [[Category: Cys-tyr cofactor]] |
| + | [[Category: Cysteine]] | ||
| + | [[Category: Iron]] | ||
| + | [[Category: Oxidoreductase]] | ||
Revision as of 07:03, 13 December 2017
Crystal structure of cysteine-bound ferrous form of the crosslinked human cysteine dioxygenase
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Categories: Cysteine dioxygenase | Li, J | Liu, A | Shin, I | Cys-tyr cofactor | Cysteine | Iron | Oxidoreductase
